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Fenoterol
CAS No. 13392-18-2
Fenoterol( —— )
Catalog No. M21615 CAS No. 13392-18-2
Fenoterol is an agonist of β2-adrenergic receptor It is classed as sympathomimetic beta agonist and asthma medication.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 55 | In Stock |
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| 2MG | 30 | In Stock |
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| 5MG | 48 | In Stock |
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| 10MG | 77 | In Stock |
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| 25MG | 155 | In Stock |
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| 50MG | 226 | In Stock |
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| 100MG | Get Quote | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameFenoterol
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NoteResearch use only, not for human use.
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Brief DescriptionFenoterol is an agonist of β2-adrenergic receptor It is classed as sympathomimetic beta agonist and asthma medication.
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DescriptionFenoterol is an agonist of β2-adrenergic receptor It is classed as sympathomimetic beta agonist and asthma medication.(In Vitro):Fenoterol (1 μM; pre-incubated 30 minutes) treatment reduces AICAR-induced AMPK activation, NF-κB activation and TNF-α release, and also significantly downregulates the elevated phosphorylation levels of AMPK.Fenoterol inhibits lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells.Fenoterol is also a potent exosome biogenesis and/or secretion activator in PC cells.(In Vivo):Fenoterol (0.7 mg/kg; intraperitoneal injection; twice a day; for 3 weeks) treatment suppresses mechanical allodynia during chronic treatment.
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In VitroFenoterol (1 μM; pre-incubated 30 minutes) treatment reduces AICAR-induced AMPK activation, NF-κB activation and TNF-α release, and also significantly downregulates the elevated phosphorylation levels of AMPK.Fenoterol inhibits lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells.Fenoterol is also a potent exosome biogenesis and/or secretion activator in PC cells. Western Blot Analysis Cell Line:THP-1 cells stimulated with AICAR Concentration:1 μM Incubation Time:Pre-incubated 30 minutes Result:Significantly downregulated the elevated phosphorylation levels of AMPK.
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In VivoFenoterol (0.7 mg/kg; intraperitoneal injection; twice a day; for 3 weeks) treatment suppresses mechanical allodynia during chronic treatment. Animal Model:Male C57BL/6J mice (6 weeks old) with neuropathy Dosage:0.7 mg/kg Administration:Intraperitoneal injection; twice a day; for 3 weeks Result:Alleviated neuropathic allodynia during chronic treatment.
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Synonyms——
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PathwayAngiogenesis
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TargetAdrenergic Receptor
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Recptorβ2-adrenergic receptor
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Research AreaCardiovascular Disease
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IndicationCongestive Heart Failure
Chemical Information
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CAS Number13392-18-2
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Formula Weight303.35
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Molecular FormulaC17H21NO4
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Purity>98% (HPLC)
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SolubilityDMSO:61 mg/mL (201.08 mM)
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SMILESCC(Cc1ccc(O)cc1)NCC(O)c1cc(O)cc(O)c1
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Chemical Name5-[1-hydroxy-2-[1-(4-hydroxyphenyl)propan-2-ylamino]ethyl]benzene-13-diol
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.R C Heelet al. Fenoterol: A Review of its Pharmacological Properties and Therapeutic Efficacy in Asthma[J]. Drugs 1978.
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