Terbutaline

CAS No. 23031-25-6

Terbutaline( —— )

Catalog No. M22981 CAS No. 23031-25-6

Terbutaline is a short-acting agonist of β2-adrenergic receptor (β2-AR) . It is an active metabolite of bambuterol.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 28 In Stock
25MG 46 In Stock
50MG 77 In Stock
100MG 128 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Terbutaline
  • Note
    Research use only, not for human use.
  • Brief Description
    Terbutaline is a short-acting agonist of β2-adrenergic receptor (β2-AR) . It is an active metabolite of bambuterol.
  • Description
    Terbutaline is a short-acting agonist of β2-adrenergic receptor (β2-AR) . It is an active metabolite of bambuterol.
  • In Vitro
    Terbutaline (0-10 μM, 1 hour) enhances MKP-1 expression in activated mouse macrophages.RT-PCR Cell Line:J774 macrophages Concentration:0-10 μM Incubation Time:1 hour Result:Enhanced MKP-1 expression in J774 macrophages in a dose-dependent manner.Western Blot Analysis Cell Line:J774 macrophages Concentration:100 nM Incubation Time:1 hour Result:Reduced the phosphorylation of p38 MAPK in J774 macrophages.
  • In Vivo
    Terbutaline (intraperitoneal injection; 0.5 mg/kg; twice a day; 20 days) treatment can improve the allodynia in ob/ob mice. Animal Model:Adult male ob/ob miceDosage:0.5 mg/kg Administration:Intraperitoneal injection; 0.5 mg/kg; twice a day; 20 days Result:Reversed the mechanical allodynia in ob/ob mice.
  • Synonyms
    ——
  • Pathway
    Angiogenesis
  • Target
    Adrenergic Receptor
  • Recptor
    β2-adrenergic receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    23031-25-6
  • Formula Weight
    225.3
  • Molecular Formula
    C12H19NO3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (1109.73 mM)
  • SMILES
    OC1=CC(C(O)CNC(C)(C)C)=CC(O)=C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Nanna, Krogh, Sebastian, et al. Terbutaline Accumulates in Blood and Urine after Daily Therapeutic Inhalation.[J]. Medicine & Science in Sports & Exercise, 2017.
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