LolCDE-IN-1( —— )

Catalog No. M21571 CAS No. 1639933-78-0

LolCDE-IN-1 is an inhibitor of the Lol proteins (LolCDE) complex with antibacterial activity.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	128	In Stock
5MG	117	In Stock
10MG	187	In Stock
25MG	312	In Stock
50MG	423	In Stock
100MG	576	In Stock
200MG	816	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

LolCDE-IN-1
Note

Research use only, not for human use.
Brief Description

LolCDE-IN-1 is an inhibitor of the Lol proteins (LolCDE) complex with antibacterial activity.
Description

LolCDE-IN-1 is an inhibitor of the Lol proteins (LolCDE) complex with antibacterial activity.
In Vitro

LolCDE-IN-1 (compound 2) inhibits the function of the LolCDE complex, which is required for transport of lipoproteins to the outer membrane.LolCDE-IN-1 inhibits E. coli ATCC 25922 and E. coli ATCC 25922 ΔtolCwith MIC with 8 μg/ml and 0.125 μg/ml.LolCDE-IN-1 inhibits bacterial growth by targeting LolCDE to block lipoprotein transport to the outer membrane.
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Bacterial
Research Area

——
Indication

——

Chemical Information

CAS Number

1639933-78-0
Formula Weight

345.37
Molecular Formula

C21H16FN3O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 41.67 mg/mL (120.65 mM)
SMILES

Fc1ccc(COc2cccc(c2)-c2n[nH]cc2-c2ccncc2)cc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Nayar AS et al. Novel antibacterial targets and compounds revealed by a high-throughput cell wall reporter assay. J Bacteriol. 2015 May;197(10):1726-34.

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