Astragaloside(b)

CAS No. 17429-69-5

Astragaloside(b)( —— )

Catalog No. M21443 CAS No. 17429-69-5

Astragaloside may protect against brain contusion and neuronal apoptosis after TBI by attenuating microglia activation in male rats. Astragalosides-induced apoptosis in NB4 cells may be associated with down-regulation of the expression of BCL-2 and NF-κB finally the relative activity of caspase-3 activated.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
50MG 45 In Stock
100MG 57 In Stock
200MG 104 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Astragaloside(b)
  • Note
    Research use only, not for human use.
  • Brief Description
    Astragaloside may protect against brain contusion and neuronal apoptosis after TBI by attenuating microglia activation in male rats. Astragalosides-induced apoptosis in NB4 cells may be associated with down-regulation of the expression of BCL-2 and NF-κB finally the relative activity of caspase-3 activated.
  • Description
    Astragaloside may protect against brain contusion and neuronal apoptosis after TBI by attenuating microglia activation in male rats. Astragalosides-induced apoptosis in NB4 cells may be associated with down-regulation of the expression of BCL-2 and NF-κB finally the relative activity of caspase-3 activated. Astragaloside has several pharmacological actions on cardiovascular system including positive inotropic anti-arrhythmia and anti-oxidant activities; it also has anti-apoptotic activity which may contribute to the improvement of clinical outcomes in treating myocarditis with pharmaceutics of Astragalus membranaceus.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    cancer
  • Indication
    Solid Tumor

Chemical Information

  • CAS Number
    17429-69-5
  • Formula Weight
    640.5
  • Molecular Formula
    C28H32O17
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    COc(cc(cc1)C(Oc(cc(cc2O)O)c2C2=O)=C2O[C@@H]([C@@H]([C@H]2O)O)O[C@H](CO[C@@H]([C@@H]([C@H]3O)O)O[C@H](CO)[C@H]3O)[C@H]2O)c1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Yin Y Y Li W P Gong H L et al. Protective Effect of Astragaloside on Focal Cerebral Ischemia/Reperfusion Injury in Rats[J]. American Journal of Chinese Medicine 2010 38(03):517-527.
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