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Pachycarpine
CAS No. 492-08-0
Pachycarpine( (+)-Sparteine )
Catalog No. M21189 CAS No. 492-08-0
Pachycarpine is a natural product extracted from scotch broom is a sodium channel blocker and a class 1a antiarrhythmic agent.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | Get Quote | In Stock |
|
| 200MG | 28 | In Stock |
|
| 500MG | 41 | In Stock |
|
| 1G | 68 | In Stock |
|
Biological Information
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Product NamePachycarpine
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NoteResearch use only, not for human use.
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Brief DescriptionPachycarpine is a natural product extracted from scotch broom is a sodium channel blocker and a class 1a antiarrhythmic agent.
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DescriptionPachycarpine is a natural product extracted from scotch broom is a sodium channel blocker and a class 1a antiarrhythmic agent.(In Vitro):(+)-Sparteine (2 μM) reduces the ACh-induced current caused by activation of nicotinic AChRs in a voltage-independent manner. (+)-Sparteine (5, 10 μM) reduces the amplitude of the excitatory postsynaptic current (EPSC) and the time constant of the EPSC decay.
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In Vitro(+)-Sparteine (2 μM) reduces the ACh-induced current caused by activation of nicotinic AChRs in a voltage-independent manner. (+)-Sparteine (5, 10 μM) reduces the amplitude of the excitatory postsynaptic current (EPSC) and the time constant of the EPSC decay.
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In Vivo——
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Synonyms(+)-Sparteine
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PathwayEndocrinology/Hormones
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TargetAChR
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RecptorAChR
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Research Area——
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Indication——
Chemical Information
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CAS Number492-08-0
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Formula Weight234.38
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Molecular FormulaC15H26N2
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Purity>98% (HPLC)
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SolubilityH2O:2.86 mg/mL (12.20 mM; Need ultrasonic)
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SMILESC1CCN2C[C@H]3C[C@H](CN4CCCC[C@H]34)[C@@H]2C1
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Chemical Name(7R-(7alpha7aalpha14alpha14abeta))-Dodecahydro-714-methano-2H6H-dipyrido (12-a:1'2'-e)(15)diazocine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Voitenko S et al. Effect of (+)-sparteine on nicotinic acetylcholine receptors in the neurons of rat superior cervical ganglion. Mol Pharmacol. 1991 Aug;40(2):180-5.
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