PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, and 44 nM, respectively.

Leonurine (hydrochloride), a major alkaloid compound extracted from?Leonurus japonicas?Houtt. (Labiatae), is considered to have antitumor roles.

Epimedin B has potential activity against osteoporosis by stimulating osteoblasts.