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TRAP-6(2TFA)
CAS No. 141136-83-6
TRAP-6(2TFA)( PAR-1 agonist peptide | Thrombin Receptor Activator Peptide 6 )
Catalog No. M21039 CAS No. 141136-83-6
TRAP-6(2TFA) is an agonist of protease-activated receptor 1 (PAR1).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 122 | In Stock |
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| 2MG | 46 | In Stock |
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| 5MG | 76 | In Stock |
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| 10MG | 122 | In Stock |
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| 25MG | 274 | In Stock |
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| 50MG | 403 | In Stock |
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| 100MG | 538 | In Stock |
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| 200MG | 768 | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameTRAP-6(2TFA)
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NoteResearch use only, not for human use.
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Brief DescriptionTRAP-6(2TFA) is an agonist of protease-activated receptor 1 (PAR1).
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DescriptionTRAP-6(2TFA) is an agonist of protease-activated receptor 1 (PAR1).
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In VitroTRAP-6 (0.01-10 μM) triggers calcium mobilization in Xenopus oocytes heterologously expressing PAR1.?TRAP-6 (0.01-10 μM; 30 min) activates human platelets.?TRAP-6 (100 μM) does not cause the platelets of rabbits or rats to change shape, aggregate, release granule contents, or form thromboxane.
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In VivoTRAP (1 mg/kg; i.v.) produces a biphasic response in blood pressure in inactin-anesthetized rats.
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SynonymsPAR-1 agonist peptide | Thrombin Receptor Activator Peptide 6
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PathwayGPCR/G Protein
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TargetPAR
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RecptorPAR-1
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Research Area——
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Indication——
Chemical Information
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CAS Number141136-83-6
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Formula Weight748.87
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Molecular FormulaC34H56N10O9
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Purity>98% (HPLC)
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SolubilityDMSO:28 mg/mL (37.39 mM) ; H2O:33.33 mg/mL (44.51 mM)
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SMILESCC(C)CC(NC(=O)C(Cc1ccccc1)NC(=O)C(N)CO)C(=O)NC(CC(C)C)C(=O)NC(CCCNC(=N)N)C(=O)NC(CC(N)=O)C(=O)O
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Chemical NameL-seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-L-asparagine
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Weber M Gerdsen F Gutensohn K et al. Enhanced platelet aggregation with TRAP-6 and collagen in platelet aggregometry in patients with venous thromboembolism[J]. Thrombosis Research 2002 107(6):0-328.
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