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RGX-104 free Acid

CAS No. 610318-54-2

RGX-104 free Acid( —— )

Catalog No. M21011 CAS No. 610318-54-2

RGX-104 free Acid is an agonist of potent liver-X nuclear hormone receptor (LXR) .

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 122 In Stock
5MG 93 In Stock
10MG 148 In Stock
25MG 297 In Stock
50MG 461 In Stock
100MG 711 In Stock
200MG 995 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    RGX-104 free Acid
  • Note
    Research use only, not for human use.
  • Brief Description
    RGX-104 free Acid is an agonist of potent liver-X nuclear hormone receptor (LXR) .
  • Description
    RGX-104 free Acid is an agonist of potent liver-X nuclear hormone receptor (LXR) .
  • In Vitro
    ——
  • In Vivo
    Animal Model:NOD SCID or RAG mice injected with 1×106 SKOV3 ovarian cancer cells.Dosage:100 mg/kg.Administration:Oral administration daily for about 60 days.Result:Robustly suppressed tumor growth and progression.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    LXRβ
  • Research Area
    Cancer
  • Indication
    Lymphoma; Solid tumours

Chemical Information

  • CAS Number
    610318-54-2
  • Formula Weight
    596.08
  • Molecular Formula
    C34H33ClF3NO3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:130 mg/mL (218.09 mM)
  • SMILES
    C[C@H](CCOc1cccc(CC(=O)O)c1)N(Cc1cccc(C(F)(F)F)c1Cl)CC(c1ccccc1)c1ccccc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Tavazoie M F Pollack I Tanqueco R et al. LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer[J]. Cell 2018:S0092867417315064.
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