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Cefotaxime

CAS No. 63527-52-6

Cefotaxime( —— )

Catalog No. M20974 CAS No. 63527-52-6

Cefotaxime is an inhibitor of penicillin binding protein.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Cefotaxime
  • Note
    Research use only, not for human use.
  • Brief Description
    Cefotaxime is an inhibitor of penicillin binding protein.
  • Description
    Cefotaxime is an inhibitor of penicillin binding protein.(In Vitro):Cefotaxime exhibits an MIC of 0.0625 mg/L for V. vulnificus CMCP6.(In Vivo):The combination of ciprofloxacin and cefotaxime is more effective in clearing V. vulnificus in vivo than previously used regimens.
  • In Vitro
    Cefotaxime exhibits an MIC of 0.0625 mg/L for V. vulnificus CMCP6.
  • In Vivo
    The combination of ciprofloxacin and cefotaxime is more effective in clearing V. vulnificus in vivo than previously used regimens. Animal Model:Female, specific pathogen free, 8-week-old BALB/c mice.Dosage:30 mg/kg. Administration:IP every 6 h.Result:The viable bacterial counts in liver were lower in mice treated with cefotaxime-plus-ciprofloxacin than in those treated with cefotaxime alone (P<0.001 at 24 h and 48 h, each).
  • Synonyms
    ——
  • Pathway
    Microbiology/Virology
  • Target
    Antifection
  • Recptor
    Antifection
  • Research Area
    ——
  • Indication
    Focus Groups

Chemical Information

  • CAS Number
    63527-52-6
  • Formula Weight
    455.46
  • Molecular Formula
    C16H17N5O7S2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:91 mg/mL (199.79 mM)
  • SMILES
    CO/N=C(\C(=O)N[C@@H]1C(=O)N2C(C(=O)O)=C(COC(C)=O)CS[C@H]12)c1csc(N)n1
  • Chemical Name
    (6R7R)-3-(acetoxymethyl)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Brogden R N Heel R C Speight T M et al. Cefuroxime: A Review of its Antibacterial Activity Pharmacological Properties and Therapeutic Use[J]. Drugs 1979 17(4):233-266.
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