Robinetin

Research use only, not for human use.

Robinetin has antioxidant and antiradical activities, inhibits EYPC membrane lipid peroxidation and HbA glycosylation with high efficiency.

Robinetin has antioxidant and antiradical activities, inhibits EYPC membrane lipid peroxidation and HbA glycosylation with high efficiency.(In Vitro):Robinetin inhibits the DNA synthesis in Proteus vulgaris, and the RNA synthesis in S. aureus. Robinetin exhibits photo-induced excited-state intramolecular proton transfer resulting in ‘two color’ (in ‘blue-violet’ and ‘yellow-green’ regions) fluorescence characteristic of flavonols, the relative contributions between the two colors being strongly modulated by the local environment of the fluorophore. Robinetin (0.1-10 μM; 1 h) inhibits HIV integrase cleavage and integration in a dose-dependent manner.(In Vivo):Pretreatment with 0.5, 12.5 or 25 mumol robinetin resulted in elevated induction of epidermal ODC by TPA at 6 h after TPA. However, treatment with 50 or 100 mumol robinetin diminished ODC induction at 6 h after TPA. Anti-mutagenicity was determined in the Salmonella typhimurium assay, Robinetin caused an 87% inhibition of mutagenicity by 2-aminoanthracene.

Robinetin (0.1-10 μM; 1 h) inhibits HIV integrase cleavage and integration in a dose-dependent manner.Robinetin inhibits the DNA synthesis in Proteus vulgaris, and the RNA synthesis in S. aureus.Robinetin (100-200 or 25 μM; 1 or 72 h) inhibitsegg yolk phosphatidylcholine (EYPC) membrane lipid peroxidation and hemoglobin A (HbA) glycosylation with high efficiency.Robinetin exhibits photo-induced excited-state intramolecular proton transfer resulting in ‘two color’ (in ‘blue-violet’ and ‘yellow-green’ regions) fluorescence characteristic of flavonols, the relative contributions between the two colors being strongly modulated by the local environment of the fluorophore.

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3,3',4',5',7-Pentahydroxyflavone

Microbiology/Virology

Antifection

Anti-infection

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490-31-3

302.238

C15H10O7

>98% (HPLC)

In Vitro:?DMSO : 120 mg/mL (397.04 mM)

Oc1ccc2c(c1)oc(-c1cc(O)c(O)c(O)c1)c(O)c2=O

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(-20℃)

With Ice Pack

≥ 2 years