ICA 110381

CAS No. 325457-99-6

ICA 110381( —— )

Catalog No. M20949 CAS No. 325457-99-6

ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 29 In Stock
10MG 32 In Stock
25MG 56 In Stock
50MG 80 In Stock
100MG 110 In Stock
200MG 161 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ICA 110381
  • Note
    Research use only, not for human use.
  • Brief Description
    ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy.
  • Description
    ICA 110381 is a KCNQ2/Q3 potassium channel opener for the treatment of epilepsy.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    Potassium Channel
  • Recptor
    KCNQ2/Q3 potassium channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    325457-99-6
  • Formula Weight
    267.11
  • Molecular Formula
    C12H8Cl2N2O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    O=C(Nc1ccc(Cl)nc1)c1ccc(Cl)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Amato G Roeloffs R Rigdon G C et al. N-Pyridyl and Pyrimidine Benzamides as KCNQ2/Q3 Potassium Channel Openers for the Treatment of Epilepsy[J]. ACS Medicinal Chemistry Letters 2011 2(6):481.
molnova catalog
related products
  • AVE1231

    AVE1231 is a TASK-1 channel blocker that inhibits TASK-1 and can be used in the study of atrial fibrillation.

  • Margatoxin

    Potent KV1.3 channel blocker (IC50 = 36 pM). Displays no effect at calcium-activated channels. Reduces VEGF-induced transmembrane calcium influxes and nitric oxide production in human endothelial cells.

  • ML418

    ML418 is a potent, selective and CNS penetrating Kir7.1 potassium channel blocker (IC50 = 310 nM), and also potently inhibits Kir6.2/SUR1.