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PTP Inhibitor II

CAS No. 2632-13-5

PTP Inhibitor II( —— )

Catalog No. M20862 CAS No. 2632-13-5

PTP inhibitor II is an inhibitor of cell-permeable protein tyrosine phosphatase (PTP) that covalently binds the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2))with Ki of128 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    PTP Inhibitor II
  • Note
    Research use only, not for human use.
  • Brief Description
    PTP inhibitor II is an inhibitor of cell-permeable protein tyrosine phosphatase (PTP) that covalently binds the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2))with Ki of128 μM.
  • Description
    PTP inhibitor II is an inhibitor of cell-permeable protein tyrosine phosphatase (PTP) that covalently binds the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2))with Ki of128 μM.
  • In Vitro
    PTP inhibitor 1 exhibits anti-angiogenic activity with an IC50 of 3.7 μM for HUVECs.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Metabolic Enzyme/Protease
  • Target
    Phosphatase
  • Recptor
    protein tyrosine phosphatase(PTP)
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2632-13-5
  • Formula Weight
    229.07
  • Molecular Formula
    C9H9BrO2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:45mg/mL(196.45mM)
  • SMILES
    COc1ccc(C(=O)CBr)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Arabaci G Guo X C Beebe K D et al. α-Haloacetophenone Derivatives As Photoreversible Covalent Inhibitors of Protein Tyrosine Phosphatases[J]. Journal of the American Chemical Society 1999 121(21):5085-5086.
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