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PTP Inhibitor II
CAS No. 2632-13-5
PTP Inhibitor II( —— )
Catalog No. M20862 CAS No. 2632-13-5
PTP inhibitor II is an inhibitor of cell-permeable protein tyrosine phosphatase (PTP) that covalently binds the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2))with Ki of128 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 50MG | 29 | In Stock |
|
| 100MG | 41 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NamePTP Inhibitor II
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NoteResearch use only, not for human use.
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Brief DescriptionPTP inhibitor II is an inhibitor of cell-permeable protein tyrosine phosphatase (PTP) that covalently binds the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2))with Ki of128 μM.
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DescriptionPTP inhibitor II is an inhibitor of cell-permeable protein tyrosine phosphatase (PTP) that covalently binds the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2))with Ki of128 μM.
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In VitroPTP inhibitor 1 exhibits anti-angiogenic activity with an IC50 of 3.7 μM for HUVECs.
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetPhosphatase
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Recptorprotein tyrosine phosphatase(PTP)
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Research Area——
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Indication——
Chemical Information
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CAS Number2632-13-5
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Formula Weight229.07
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Molecular FormulaC9H9BrO2
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Purity>98% (HPLC)
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SolubilityDMSO:45mg/mL(196.45mM)
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SMILESCOc1ccc(C(=O)CBr)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Arabaci G Guo X C Beebe K D et al. α-Haloacetophenone Derivatives As Photoreversible Covalent Inhibitors of Protein Tyrosine Phosphatases[J]. Journal of the American Chemical Society 1999 121(21):5085-5086.
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