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Home - Products - Membrane Transporter/Ion Channel - iGluR - CX546

CX546

CAS No. 215923-54-9

CX546( —— )

Catalog No. M20795 CAS No. 215923-54-9

CX546 is an AMPA receptor modulator. CX546 enhances cognitive function in rats. It has also been proposed as a treatment for schizophrenia.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    CX546
  • Note
    Research use only, not for human use.
  • Brief Description
    CX546 is an AMPA receptor modulator. CX546 enhances cognitive function in rats. It has also been proposed as a treatment for schizophrenia.
  • Description
    CX546 is an AMPA receptor modulator. CX546 enhances cognitive function in rats. It has also been proposed as a treatment for schizophrenia.
  • In Vitro
    ——
  • In Vivo
    Treatment with the ampakine CX614 (intraperitoneal injection) markedly and reversibly increase brain-derived neurotrophic factor (BDNF) mRNA and protein levels in cultured rat entorhinal/hippocampal slices.
  • Synonyms
    ——
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    iGluR
  • Recptor
    AMPAR
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    215923-54-9
  • Formula Weight
    247.29
  • Molecular Formula
    C14H17NO3
  • Purity
    >98% (HPLC)
  • Solubility
    Ethanol:100 mg/mL (404.38 mM; Need ultrasonic);H2O:2 mg/mL (8.09 mM; Need ultrasonic)
  • SMILES
    O=C(c1ccc2c(c1)OCCO2)N1CCCCC1
  • Chemical Name
    23-Dihydro-14-benzodioxin-7-yl-(1-piperidyl)methanone

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Nagarajan N Quast C Boxall A R et al. Mechanism and impact of allosteric AMPA receptor modulation by the AmpakineTM CX546[J]. Neuropharmacology 2001 41(6):0-663.
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