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CCMI
CAS No. 917837-54-8
CCMI( AVL-3288 )
Catalog No. M20774 CAS No. 917837-54-8
CCMI is a potent and selective modulator of α7 nAChR-positive allosteric.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 51 | In Stock |
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| 2MG | 31 | In Stock |
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| 5MG | 46 | In Stock |
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| 10MG | 77 | In Stock |
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| 25MG | 130 | In Stock |
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| 50MG | 182 | In Stock |
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| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCCMI
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NoteResearch use only, not for human use.
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Brief DescriptionCCMI is a potent and selective modulator of α7 nAChR-positive allosteric.
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DescriptionCCMI is a potent and selective modulator of α7 nAChR-positive allosteric.
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In VitroCCMI (Compound 6) is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs.
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In Vivo——
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SynonymsAVL-3288
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PathwayEndocrinology/Hormones
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TargetAChR
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RecptornAChR
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Research Area——
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Indication——
Chemical Information
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CAS Number917837-54-8
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Formula Weight388.25
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Molecular FormulaC19H15Cl2N3O2
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/mL (257.57 mM)
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SMILESCc1cc(/C(=C/Nc2ccc(Cl)cc2)C(=O)Nc2ccc(Cl)cc2)on1
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Chemical Name(Z)-3-(4-Chloroanilino)-N-(4-chlorophenyl)-2-(3-methylisoxazol-5-yl)prop-2-enamide
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ng H J Whittemore E R Tran M B et al. Nootropic ?7 nicotinic receptor allosteric modulator derived from GABAA receptor modulators[J]. Proceedings of the National Academy of Sciences 2007 104(19):8059-8064.
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