CCMI( AVL-3288 )

Catalog No. M20774 CAS No. 917837-54-8

CCMI is a potent and selective modulator of α7 nAChR-positive allosteric.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	51	In Stock
2MG	31	In Stock
5MG	46	In Stock
10MG	77	In Stock
25MG	130	In Stock
50MG	182	In Stock
100MG	Get Quote	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

CCMI
Note

Research use only, not for human use.
Brief Description

CCMI is a potent and selective modulator of α7 nAChR-positive allosteric.
Description

CCMI is a potent and selective modulator of α7 nAChR-positive allosteric.
In Vitro

CCMI (Compound 6) is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs.
In Vivo

——
Synonyms

AVL-3288
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

nAChR
Research Area

——
Indication

——

Chemical Information

CAS Number

917837-54-8
Formula Weight

388.25
Molecular Formula

C19H15Cl2N3O2
Purity

>98% (HPLC)
Solubility

DMSO:100 mg/mL (257.57 mM)
SMILES

Cc1cc(/C(=C/Nc2ccc(Cl)cc2)C(=O)Nc2ccc(Cl)cc2)on1
Chemical Name

(Z)-3-(4-Chloroanilino)-N-(4-chlorophenyl)-2-(3-methylisoxazol-5-yl)prop-2-enamide

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Ng H J Whittemore E R Tran M B et al. Nootropic ?7 nicotinic receptor allosteric modulator derived from GABAA receptor modulators[J]. Proceedings of the National Academy of Sciences 2007 104(19):8059-8064.

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