Cart
sales@molnova.com
CCMI
CAS No. 917837-54-8
CCMI( AVL-3288 )
Catalog No. M20774 CAS No. 917837-54-8
CCMI is a potent and selective modulator of α7 nAChR-positive allosteric.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 51 | In Stock |
|
| 2MG | 31 | In Stock |
|
| 5MG | 46 | In Stock |
|
| 10MG | 77 | In Stock |
|
| 25MG | 130 | In Stock |
|
| 50MG | 182 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCCMI
-
NoteResearch use only, not for human use.
-
Brief DescriptionCCMI is a potent and selective modulator of α7 nAChR-positive allosteric.
-
DescriptionCCMI is a potent and selective modulator of α7 nAChR-positive allosteric.
-
In VitroCCMI (Compound 6) is a potent and selective α7 nAChR-positive allosteric modulator, does not bind to or activate α7 nAChRs via the orthosteric site, and causes significant positive modulation of agonist-induced currents at α7 nAChRs.
-
In Vivo——
-
SynonymsAVL-3288
-
PathwayEndocrinology/Hormones
-
TargetAChR
-
RecptornAChR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number917837-54-8
-
Formula Weight388.25
-
Molecular FormulaC19H15Cl2N3O2
-
Purity>98% (HPLC)
-
SolubilityDMSO:100 mg/mL (257.57 mM)
-
SMILESCc1cc(/C(=C/Nc2ccc(Cl)cc2)C(=O)Nc2ccc(Cl)cc2)on1
-
Chemical Name(Z)-3-(4-Chloroanilino)-N-(4-chlorophenyl)-2-(3-methylisoxazol-5-yl)prop-2-enamide
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Ng H J Whittemore E R Tran M B et al. Nootropic ?7 nicotinic receptor allosteric modulator derived from GABAA receptor modulators[J]. Proceedings of the National Academy of Sciences 2007 104(19):8059-8064.
molnova catalog
related products
-
Dehydroevodiamine hy...
Dehydroevodiamine (DHE) a natural compound isolated from Evodia rutaecarpa can inhibit AChE. It has hypotensive and neuroprotective effects and modulates nitric oxide production.
-
A 582941 HCl (848591...
A-582941 is a alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing propertiesA-582941 was found to exhibit high-affinity binding and partial agonism at alpha7 nAChRs, with acceptable pharmacokinetic properties and excellent distribution to the central nervous system (CNS).
-
DL-trihexyphenidyl h...
One of the centrally acting muscarinic antagonists used for treatment of parkinsonia disorders and drug-induced extrapyramidal movement disorders and as an antispasmodic.
