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CAY10471 Racemate
CAS No. 844639-57-2
CAY10471 Racemate( TM30089 Racemate )
Catalog No. M20762 CAS No. 844639-57-2
CAY 10471 is a potent highly selective CRTH2/DP 2 receptor antagonist. CAY10471 binds to the human CRTH2/DP2 DP1 and TP receptors( Ki values of 0.6 1200 and >10000 nMrespectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 45 | In Stock |
|
| 5MG | 41 | In Stock |
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| 10MG | 65 | In Stock |
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| 25MG | 136 | In Stock |
|
| 50MG | 198 | In Stock |
|
| 100MG | 294 | In Stock |
|
| 200MG | 425 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameCAY10471 Racemate
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NoteResearch use only, not for human use.
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Brief DescriptionCAY 10471 is a potent highly selective CRTH2/DP 2 receptor antagonist. CAY10471 binds to the human CRTH2/DP2 DP1 and TP receptors( Ki values of 0.6 1200 and >10000 nMrespectively).
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DescriptionCAY 10471 is a potent highly selective CRTH2/DP 2 receptor antagonist. CAY10471 binds to the human CRTH2/DP2 DP1 and TP receptors( Ki values of 0.6 1200 and >10000 nMrespectively).
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In VitroCAY10471 Racemate (Compound 13) inhibits PGD2-induced inositol phosphate or cAMP formation, suppresses β-arrestin translocation with IC50s of 12 and 3 nM, respectively.
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In Vivo——
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SynonymsTM30089 Racemate
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PathwayCell Cycle/DNA Damage
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TargetGPR
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RecptorCRTh2 (DP2) receptor
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Research Area——
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Indication——
Chemical Information
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CAS Number844639-57-2
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Formula Weight416.47
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Molecular FormulaC21H21FN2O4S
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Purity>98% (HPLC)
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SolubilityDMSO:150 mg/mL (360.17 mM)
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SMILESCN(C1CCc2c(C1)c1ccccc1n2CC(O)=O)S(=O)(=O)c1ccc(F)cc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Ulven T Kostenis E . Minor Structural Modifications Convert the Dual TP/CRTH2 Antagonist Ramatroban into a Highly Selective and Potent CRTH2 Antagonist[J]. Journal of Medicinal Chemistry 2005 48(4):897-900.
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