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LY 43578
CAS No. 26766-35-8
LY 43578( —— )
Catalog No. M34324 CAS No. 26766-35-8
LY 43578 is an orally active aromatase inhibitor. LY43578 could inhibit O-demethylation of P-450-dependent p-nitroanisole and N-demethylation of ethylmorphine (IC50 of 0.3 and 5 μm, respectively) in rat liver microsomes.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 46 | In Stock |
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| 10MG | 73 | In Stock |
|
| 25MG | 117 | In Stock |
|
| 50MG | 172 | In Stock |
|
| 100MG | 250 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameLY 43578
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NoteResearch use only, not for human use.
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Brief DescriptionLY 43578 is an orally active aromatase inhibitor. LY43578 could inhibit O-demethylation of P-450-dependent p-nitroanisole and N-demethylation of ethylmorphine (IC50 of 0.3 and 5 μm, respectively) in rat liver microsomes.
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DescriptionLY43578 is anorally active aromatase inhibitor. LY43578 inhibits P-450-dependent p-nitroanisole O-demethylation and ethylmorphine N-demethylation in hepatic microsomes isolated from rat, with the IC50 of 0.3 and 5 μΜ, respectively. LY43578 can be used for neurological disorder study.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayMetabolic Enzyme/Protease
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TargetP450
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RecptorP450 | Aromatase
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Research Area——
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Indication——
Chemical Information
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CAS Number26766-35-8
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Formula Weight331.2
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Molecular FormulaC17H12Cl2N2O
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Purity>98% (HPLC)
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Solubility——
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SMILESC(O)(C1=CC=C(Cl)C=C1)(C2=CC=C(Cl)C=C2)C=3C=NC=NC3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lindstrom TD, et al. Disposition of the aromatase inhibitor LY56110 and associated induction and inhibition studies in rats, dogs, and monkeys. Fundam Appl Toxicol. 1987;8(4):595-604.?
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