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Ralfinamide

CAS No. 133865-88-0

Ralfinamide( FCE-26742A | Priralfinamide )

Catalog No. M20711 CAS No. 133865-88-0

Ralfinamide is an orally available Na-channel blocker for the treatment of neuropathic pain and other pain conditions.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 31 In Stock
10MG 29 In Stock
25MG 59 In Stock
50MG 107 In Stock
100MG 164 In Stock
200MG 242 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
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Biological Information

  • Product Name
    Ralfinamide
  • Note
    Research use only, not for human use.
  • Brief Description
    Ralfinamide is an orally available Na-channel blocker for the treatment of neuropathic pain and other pain conditions.
  • Description
    Ralfinamide is an orally available Na-channel blocker for the treatment of neuropathic pain and other pain conditions.(In Vivo):Ralfinamide (30 mg/kg, 60 mg/kg; p.o.; twice daily; 42 days) treated with Ralfinamide (80 mg/kg; p.o.; twice daily; 7 days) preoperatively suppresses neuropathic pain.
  • In Vitro
    ——
  • In Vivo
    Ralfinamide (30 mg/kg, 60 mg/kg; p.o.; twice daily; 42 days) treated with Ralfinamide (80 mg/kg; p.o.; twice daily; 7 days) preoperatively suppresses neuropathic pain. Animal Model:81 adult male Sprague–Dawley male rats (260–460 g)Dosage:80 mg/kg (7 days preoperatively), 30 mg/kg, 60 mg/kg (postoperative)Administration:Oral gavage; twice daily; until postoperative day 42Result:Suppressed neuropathic pain.
  • Synonyms
    FCE-26742A | Priralfinamide
  • Pathway
    Membrane Transporter/Ion Channel
  • Target
    Sodium Channel
  • Recptor
    Na-channel
  • Research Area
    Neurological Disease
  • Indication
    Neuropathic pain

Chemical Information

  • CAS Number
    133865-88-0
  • Formula Weight
    302.34
  • Molecular Formula
    C17H19FN2O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:125 mg/mL (413.44 mM)
  • SMILES
    C[C@H](NCc1ccc(OCc2ccccc2F)cc1)C(N)=O
  • Chemical Name
    (2S)-2-(4-(2-Fluorobenzyloxy)benzylamino)propanamide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Liang X Yu G Su R . Effects of ralfinamide in models of nerve injury and chemotherapy-induced neuropathic pain[J]. European journal of pharmacology 2018 823:27-34.
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