Cart
sales@molnova.com
2-Iminobiotin
CAS No. 13395-35-2
2-Iminobiotin( Guanidinobiotin | 2-IMINOBIOTIN HYDROBROMIDE )
Catalog No. M20639 CAS No. 13395-35-2
2-Iminobiotin is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS; Ki of 21.8 and 37.5 μM for mouse iNOS and rat nNOS respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 55 | In Stock |
|
| 10MG | 82 | In Stock |
|
| 25MG | 148 | In Stock |
|
| 50MG | 222 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Name2-Iminobiotin
-
NoteResearch use only, not for human use.
-
Brief Description2-Iminobiotin is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS; Ki of 21.8 and 37.5 μM for mouse iNOS and rat nNOS respectively).
-
Description2-Iminobiotin is a cyclic guanidino analog of biotin that acts as a reversible inhibitor of inducible nitric oxide synthase (iNOS) and neuronal NOS (nNOS; Ki of 21.8 and 37.5 μM for mouse iNOS and rat nNOS respectively).
-
In VitroApplication of low concentrations of 2-Iminobiotin (2-IB; 10 ng/mL and 30 ng/mL) superimposed on hypothermia abrogates the hypoxia-induced lactate dehydrogenase (LDH) increase, resulting in LDH levels that were not different from the normoxia control.
-
In Vivo——
-
SynonymsGuanidinobiotin | 2-IMINOBIOTIN HYDROBROMIDE
-
PathwayImmunology/Inflammation
-
TargetNOS
-
RecptorNOS
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number13395-35-2
-
Formula Weight243.33
-
Molecular FormulaC10H17N3O2S??
-
Purity>98% (HPLC)
-
SolubilityDMSO:12.5 mg/mL (51.37 mM)
-
SMILES[H][C@]12CS[C@@H](CCCCC(O)=O)[C@@]1([H])NC(=N)N2
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Zitta K Peeters-Scholte C Sommer L et al. 2-Iminobiotin Superimposed on Hypothermia Protects Human Neuronal Cells from Hypoxia-Induced Cell Damage: An in Vitro Study[J]. Frontiers in Pharmacology 2018 8:971.
molnova catalog
related products
-
6-O-Cinnamoyl harpag...
6'-O-Cinnamoyl harpagide is an iridoid glycoside isolated from the roots of Scrophularia ningpoensis.
-
ZL-006
ZL-006 (ZL 006, ZL006) is a brain penetrant small molecule inhibitor of PSD-95/nNOS interaction that prevents glutamate-induced excitotoxicity and cerebral ischemic damage in vivo.
-
Soyasaponin Ab
Soyasaponin Ab may represent a viable candidate for effective vaccine adjuvant, TLR4 receptor dependent pathway may be involved in immune stimulatory effects of soyasaponin Ab.
