Alpha-Methyldopa Sesquihydrate( MK-351 hydrate | Methyldopa hydrate | Methyldopa Sesquihydrate | L-(-)-α-Methyldopa hydrate )

Catalog No. M20585 CAS No. 41372-08-1

Alpha-Methyldopa Sesquihydrate is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. It inhibits the sympathetic nervous system decreases production of dopamine norepinephrine and epinephrine and exhibits NO-dependent sedative activity.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	28	In Stock
100MG	Get Quote	In Stock
200MG	Get Quote	In Stock
500MG	27	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

Alpha-Methyldopa Sesquihydrate
Note

Research use only, not for human use.
Brief Description

Alpha-Methyldopa Sesquihydrate is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. It inhibits the sympathetic nervous system decreases production of dopamine norepinephrine and epinephrine and exhibits NO-dependent sedative activity.
Description

Alpha-Methyldopa Sesquihydrate is a DOPA decarboxylase inhibitor and indirect α2-adrenergic receptor agonist used to treat hypertension. It inhibits the sympathetic nervous system decreases production of dopamine norepinephrine and epinephrine and exhibits NO-dependent sedative activity.(In Vivo):Methyldopa hydrate (L-(-)-α-Methyldopa hydrate; 200 mg/kg; i.p.) decreases the hyperglycemic response in the first 2 hr after Dieldrin treatment.
In Vitro

——
In Vivo

Methyldopa hydrate (L-(-)-α-Methyldopa hydrate; 200 mg/kg; i.p.) decreases the hyperglycemic response in the first 2 hr after Dieldrin treatment. Animal Model:60-day-old male rats Dosage:200 mg/kg Administration: i.p.Result:Decreased the plasma concentration of glucose in Dieldrin-exposed rats by 24% during the 30 min following its administration.
Synonyms

MK-351 hydrate | Methyldopa hydrate | Methyldopa Sesquihydrate | L-(-)-α-Methyldopa hydrate
Pathway

GPCR/G Protein
Target

Dopamine Receptor
Recptor

DOPA decarboxylase
Research Area

——
Indication

——

Chemical Information

CAS Number

41372-08-1
Formula Weight

238.24
Molecular Formula

C10H13NO4·3/2H?O
Purity

>98% (HPLC)
Solubility

DMSO:33.33 mg/mL (139.90 mM)
SMILES

O.O.O.C[C@](N)(Cc1ccc(O)c(O)c1)C(O)=O.C[C@](N)(Cc1ccc(O)c(O)c1)C(O)=O
Chemical Name

(S)-2-amino-3-(34-dihydroxyphenyl)-2-methylpropanoic acid sesquihydrate

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Baila M R Cintas J A . [The use of the combination of L-alpha-methyldopa and dichlorothiazide in the treatment of arterial hypertension][J]. El Día Médico 1962 34:2422.

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

Product			Quantity Required*
Name *			E-mail Address *
Organization *			Phone Number
Remarks