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2-Ketoglutaric acid

CAS No. 328-50-7

2-Ketoglutaric acid( —— )

Catalog No. M20576 CAS No. 328-50-7

2-Ketoglutaric acid is a key molecule in the tricarboxylic acid cycleis also connected to glutamic acid and glutamine metabolisms through the transamination reactions.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    2-Ketoglutaric acid
  • Note
    Research use only, not for human use.
  • Brief Description
    2-Ketoglutaric acid is a key molecule in the tricarboxylic acid cycleis also connected to glutamic acid and glutamine metabolisms through the transamination reactions.
  • Description
    2-Ketoglutaric acid is a key molecule in the tricarboxylic acid cycleis also connected to glutamic acid and glutamine metabolisms through the transamination reactions.
  • In Vitro
    2-Ketoglutaric acid (Alpha-Ketoglutaric acid) has other physiological capabilities including reduction of ammonia level formed in the lung and general ammonia detoxification, protective role against lipid peroxidation and neuroprotective effect against cyanide poisoning.2-Ketoglutaric acid acts as precursor for the synthesis of amino acids and nucleotides.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Human Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    328-50-7
  • Formula Weight
    146.1
  • Molecular Formula
    C5H6O5
  • Purity
    >98% (HPLC)
  • Solubility
    H2O:50 mg/mL (342.23 mM; Need ultrasonic)
  • SMILES
    OC(=O)CCC(=O)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Rocchiccioli F Leroux J P Cartier P H . Microdetermination of 2-ketoglutaric acid in plasma and cerebrospinal fluid by capillary gas chromatography mass spectrometry; application to pediatrics[J]. Biomedical Mass Spectrometry 1984 11(1):24-28.
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