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LXS196
CAS No. 1874276-76-2
LXS196( —— )
Catalog No. M20328 CAS No. 1874276-76-2
LXS196 is a potent selective and orally active protein kinase C (PKC) inhibitor(IC50 values of 1.9 nM 0.4 nM and 3.1 μM for PKCα PKCθ and GSK3β respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 138 | In Stock |
|
| 5MG | 131 | In Stock |
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| 10MG | 188 | In Stock |
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| 25MG | 351 | In Stock |
|
| 50MG | 492 | In Stock |
|
| 100MG | 724 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameLXS196
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NoteResearch use only, not for human use.
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Brief DescriptionLXS196 is a potent selective and orally active protein kinase C (PKC) inhibitor(IC50 values of 1.9 nM 0.4 nM and 3.1 μM for PKCα PKCθ and GSK3β respectively).
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DescriptionLXS196 is a potent selective and orally active protein kinase C (PKC) inhibitor(IC50 values of 1.9 nM 0.4 nM and 3.1 μM for PKCα PKCθ and GSK3β respectively).
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In Vitro——
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In VivoAnimal Model:Mice implanted with 92.1 GNAQ mutant uveal melanoma cells.Dosage:15, 30, 75, 150 mg/kg Administration:P.O. (bid) for 35 days Result:Dose-dependently suppressed the tumor growth.
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Synonyms——
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PathwayAngiogenesis
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TargetPKC
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RecptorPKC
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Research AreaCancer
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IndicationColorectal Cancer; Malignant melanoma; Solid tumours; Uveal melanoma
Chemical Information
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CAS Number1874276-76-2
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Formula Weight472.47
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Molecular FormulaC22H23F3N8O?
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Purity>98% (HPLC)
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SolubilityDMSO:100 mg/mL (211.65 mM)
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SMILESCC1(N)CCN(CC1)c1cccnc1NC(=O)c1nc(cnc1N)-c1ncccc1C(F)(F)F
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Protein Kinase C Inhibitor LXS196.
molnova catalog
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