ML367

CAS No. 381168-77-0

ML367( —— )

Catalog No. M20178 CAS No. 381168-77-0

ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization and acts as a probe molecule that has low micromolar inhibitory activity.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 51 In Stock
10MG 76 In Stock
25MG 125 In Stock
50MG 178 In Stock
100MG 332 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ML367
  • Note
    Research use only, not for human use.
  • Brief Description
    ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization and acts as a probe molecule that has low micromolar inhibitory activity.
  • Description
    ML367 is a potent inhibitor of ATPase family AAA domain-containing protein 5 (ATAD5) stabilization and acts as a probe molecule that has low micromolar inhibitory activity.
  • In Vitro
    Western Blot Analysis Cell Line:HEK293T cells Concentration:0-40 μM in the presence or absence of 20 μM 5-Furd Incubation Time:16 hours Result:Inhibited the increased ATAD5 protein levels induced by 5-Furd.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ATAD5
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    381168-77-0
  • Formula Weight
    334.32
  • Molecular Formula
    C19H12F2N4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:120 mg/mL?(358.94 mM)
  • SMILES
    Fc1ccc(Nc2nc(nc3ccccc23)-c2ccncc2)cc1F
  • Chemical Name
    (S)-9b-(4-Chlorophenyl)-1-(34-difluorobenzoyl)-23-dihydro-1H-imidazo[21-a]isoindol-5(9bH)-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Rohde JM et al. Discovery of ML367 inhibitor of ATAD5 stabilization. Probe Reports from the NIH Molecular Libraries Program.
molnova catalog
related products
  • Flagelin 22 TFA (304...

    Flagelin 22 TFA (Flagellin 22 TFA), a fragment of bacterial flagellin, is an effective elicitor in both plants and algae.

  • Dexamethasone Sodium...

    Dexamethasone, an interleukin receptor modulator, has anti-inflammatory and immunosuppressant effects. It belongs to a potent glucocorticoid class of steroid synthetic drugs.

  • D-(+)-Maltose monohy...

    A dextrodisaccharide from malt and starch. It is used as a sweetening agent and fermentable intermediate in brewing.