Cart
sales@molnova.com
Cycloguanil hydrochloride
CAS No. 152-53-4
Cycloguanil hydrochloride( Chloroguanide Triazine )
Catalog No. M20150 CAS No. 152-53-4
Cycloguanil is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodium and human forms respectively).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 33 | In Stock |
|
| 5MG | 29 | In Stock |
|
| 10MG | 43 | In Stock |
|
| 25MG | 70 | In Stock |
|
| 50MG | 99 | In Stock |
|
| 100MG | 145 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCycloguanil hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionCycloguanil is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodium and human forms respectively).
-
DescriptionCycloguanil is an active metabolite of the antimalarial compound proguanil. It acts as an inhibitor of dihydrofolate reductase (Kis: 0.3 and 1.5 nM for Plasmodium and human forms respectively).
-
In Vitro——
-
In Vivo——
-
SynonymsChloroguanide Triazine
-
PathwayMicrobiology/Virology
-
TargetParasite
-
RecptorParasite
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number152-53-4
-
Formula Weight288.18
-
Molecular FormulaC11H14ClN5.ClH
-
Purity>98% (HPLC)
-
SolubilityDMSO: 20 mg/mL (69.4 mM);Water: 5 mg/mL (17.35 mM)
-
SMILESCl.CC1(C)N=C(N)N=C(N)N1c1ccc(Cl)cc1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Wright JD et al. The role of S-mephenytoin hydroxylase (CYP2C19) in the metabolism of the antimalarial biguanides. Br J Clin Pharmacol. 1995 Apr;39(4):441-4.
molnova catalog
related products
-
Chlorin E6
Chlorin E6 (CE6) is a second-generation photosensitizer with antitumor activity when used in combination with irradiation.
-
Artefenomel
Artefenomel (OZ439) is a novel, next-generation antimalarial ozonide that demonstrates high potentcy against P. falciparum in vitro and P. berghei in vivo (K1/NF54, IC50=2.0/3.2 nM).
-
Closantel
A veterinary anthelmintic with known proton ionophore activities; is identified as a potent and specific inhibitor of filarial chitinases.
