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Antitrypanosomal agent 1
CAS No. 75144-12-6
Antitrypanosomal agent 1( —— )
Catalog No. M26057 CAS No. 75144-12-6
Antitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 100MG | 68 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameAntitrypanosomal agent 1
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NoteResearch use only, not for human use.
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Brief DescriptionAntitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM).
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DescriptionAntitrypanosomal agent 1 is a potent and selective trypanothione reductase (TR) inhibitor (IC50: 3.3 μM). Antitrypanosomal agent 1 inhibits glutathione reductase (IC50: 64.8 μM) and T. brucei (EC50: 1 μM).
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In VitroAntitrypanosomal agent 1 (compound 8a) has an selectivity for TR (GR IC50/TR IC50) of 20.
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In Vivo——
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Synonyms——
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PathwayMicrobiology/Virology
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TargetParasite
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Recptor——
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Research Area——
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Indication——
Chemical Information
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CAS Number75144-12-6
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Formula Weight282.59
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Molecular FormulaC11H14Cl3NO
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (88.47 mM)
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SMILESCl.CN(C)CCC(=O)c1ccc(Cl)c(Cl)c1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Aranya Manosroi, et al. Melanogenesis of methyl myristate loaded niosomes in B16F10 melanoma cells. J Biomed Nanotechnol. 2013 Apr;9(4):626-38.
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