MRT68921 HCl

CAS No. 2070014-87-6

MRT68921 HCl( —— )

Catalog No. M20090 CAS No. 2070014-87-6

MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM respectively).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 58 In Stock
5MG 57 In Stock
10MG 90 In Stock
25MG 188 In Stock
50MG 333 In Stock
100MG 415 In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    MRT68921 HCl
  • Note
    Research use only, not for human use.
  • Brief Description
    MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM respectively).
  • Description
    MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM respectively).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Autophagy
  • Target
    Autophagy
  • Recptor
    ULK1| ULK2
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2070014-87-6
  • Formula Weight
    471.04
  • Molecular Formula
    C25H34N6O·HCl
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mg/mL;Water: 10 mg/mL
  • SMILES
    Cl.CN1CCc2cc(Nc3ncc(C4CC4)c(NCCCNC(=O)C4CCC4)n3)ccc2C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Petherick KJ et al. Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy. J Biol Chem. 2015 May 1;290(18):11376-83.
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