MRT68921 HCl( —— )

Catalog No. M20090 CAS No. 2070014-87-6

MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM respectively).

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Biological Information

Product Name

MRT68921 HCl
Note

Research use only, not for human use.
Brief Description

MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM respectively).
Description

MRT68921 hydrochloride is a potent inhibitor of both ULK1 and ULK2 (IC50s: 2.9 and 1.1 nM respectively).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Autophagy
Target

Autophagy
Recptor

ULK1| ULK2
Research Area

——
Indication

——

Chemical Information

CAS Number

2070014-87-6
Formula Weight

471.04
Molecular Formula

C25H34N6O·HCl
Purity

>98% (HPLC)
Solubility

DMSO: 10 mg/mL;Water: 10 mg/mL
SMILES

Cl.CN1CCc2cc(Nc3ncc(C4CC4)c(NCCCNC(=O)C4CCC4)n3)ccc2C1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Petherick KJ et al. Pharmacological inhibition of ULK1 kinase blocks mammalian target of rapamycin (mTOR)-dependent autophagy. J Biol Chem. 2015 May 1;290(18):11376-83.

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