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3-Chloro-L-Tyrosine
CAS No. 7423-93-0
3-Chloro-L-Tyrosine( 3-Chlorotyrosine | Chlorotyrosine )
Catalog No. M20026 CAS No. 7423-93-0
3-Chlorotyrosine a specific marker of myeloperoxidase-catalyzed oxidation is markedly elevated in low-density lipoprotein isolated from human atherosclerotic intima. In particular myeloperoxidase halogenates tyrosine residues in plasma proteins and generates 3-chlorotyrosine (CY).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product Name3-Chloro-L-Tyrosine
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NoteResearch use only, not for human use.
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Brief Description3-Chlorotyrosine a specific marker of myeloperoxidase-catalyzed oxidation is markedly elevated in low-density lipoprotein isolated from human atherosclerotic intima. In particular myeloperoxidase halogenates tyrosine residues in plasma proteins and generates 3-chlorotyrosine (CY).
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Description3-Chlorotyrosine a specific marker of myeloperoxidase-catalyzed oxidation is markedly elevated in low-density lipoprotein isolated from human atherosclerotic intima. In particular myeloperoxidase halogenates tyrosine residues in plasma proteins and generates 3-chlorotyrosine (CY). The detection of free chlorotyrosine in blood or urine arises from the degradation of these chlorinated proteins. CY concentrations may be useful for monitoring the activation of neutrophils in asthmatic patients.
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In Vitro——
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In Vivo——
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Synonyms3-Chlorotyrosine | Chlorotyrosine
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number7423-93-0
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Formula Weight215.63
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Molecular FormulaC9H10ClNO3
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Purity>98% (HPLC)
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SolubilityWater:41.7 mM
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SMILESN[C@@H](Cc1ccc(O)c(Cl)c1)C(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Hazen SL et al. 3-Chlorotyrosine a specific marker of myeloperoxidase-catalyzed oxidation is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima. J Clin Invest. 1997 May 1;99(9):2075-81.
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