NADH disodium salt hydrate

CAS No. 606-68-8

NADH disodium salt hydrate( Disodium NADH | NADH disodium salt )

Catalog No. M19981 CAS No. 606-68-8

NADH is the reduced form of nicotinamide adenine dinucleotide (NAD) that can donate electrons as part of a reducing reaction. In that process NADH becomes oxidized to produce NAD+. A variety of enzymes use NADH plus H+ to reduce substrates generating NAD+ as well as the reduced product.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
500MG 43 In Stock
1G 52 In Stock

Biological Information

  • Product Name
    NADH disodium salt hydrate
  • Note
    Research use only, not for human use.
  • Brief Description
    NADH is the reduced form of nicotinamide adenine dinucleotide (NAD) that can donate electrons as part of a reducing reaction. In that process NADH becomes oxidized to produce NAD+. A variety of enzymes use NADH plus H+ to reduce substrates generating NAD+ as well as the reduced product.
  • Description
    NADH is the reduced form of nicotinamide adenine dinucleotide (NAD) that can donate electrons as part of a reducing reaction. In that process NADH becomes oxidized to produce NAD+. A variety of enzymes use NADH plus H+ to reduce substrates generating NAD+ as well as the reduced product.
  • In Vitro
    ——
  • In Vivo
    Animal Model:Male ICR mice Dosage:5 μmol/mouse Administration:Intraperitoneal injection or oral administration, once Result:Produced significant increases in urinary excretions of nicotinamide (Nam) with intraperitoneal injection. Oral administration did not produce any increases in Nam or its metabolites.Animal Model:Male C57BL/6J mice Dosage:500 mg/kg Administration:Intragastric administration, 15 min before ethanol administration Result:Significantly increased blood acetaldehyde levels in mice administered with alcohol between 30 min and two hours. Significantly reduced the acetaldehyde in the blood after two hours. Inhibited the decrease of NAD+/NADH redox ratio in hepatocytes.
  • Synonyms
    Disodium NADH | NADH disodium salt
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    606-68-8
  • Formula Weight
    709.4
  • Molecular Formula
    C21H27N7Na2O14P2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:42.3 mM
  • SMILES
    [Na+].[Na+].NC(=O)C1=CN(C=CC1)[C@@H]1O[C@H](COP([O-])(=O)OP([O-])(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Kim MS et al. Enzymatic properties of the membrane-bound NADH oxidase system in the aerobic respiratory chain of Bacillus cereus. J Biochem Mol Biol. 2004 Nov 30;37(6):753-6.
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