Anisotropine Methylbromide

CAS No. 80-50-2

Anisotropine Methylbromide( —— )

Catalog No. M19949 CAS No. 80-50-2

Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 29 In Stock
10MG 38 In Stock
25MG 70 In Stock
50MG 114 In Stock
100MG 183 In Stock
200MG Get Quote In Stock
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Biological Information

  • Product Name
    Anisotropine Methylbromide
  • Note
    Research use only, not for human use.
  • Brief Description
    Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion.
  • Description
    Anisotropine Methylbromide is an anticholinergic agent and has been used for relief of gastrointestinal spasm and for the suppression of gastric acid secretion.(In Vivo):Anisotropine bromide (intravenous injection, 0.5 μM and 0.1 mL, once) can block acetylcholine-induced vocalization, intestinal spasm and intestinal contractions in conscious or anesthetized dogs.
  • In Vitro
    ——
  • In Vivo
    Anisotropine bromide (intravenous injection, 0.5 μM and 0.1 mL, once) can block acetylcholine-induced vocalization, intestinal spasm and intestinal contractions in conscious or anesthetized dogs. Animal Model:Dogs weighing 2.5 to 5.0 kg Dosage:0.5 μM, 0.1 mL Administration:Intravenous injection; once Result:Inhibited the acetylcholine-induced vocalization with maximum inhibition of 85.1% and the acetylcholine-induced intestinal spasm with maximum inhibition of 79%.
  • Synonyms
    ——
  • Pathway
    Endocrinology/Hormones
  • Target
    AChR
  • Recptor
    Cholinergic|DP1|IP|EP2
  • Research Area
    Metabolic Disease
  • Indication
    peptic ulcer

Chemical Information

  • CAS Number
    80-50-2
  • Formula Weight
    362.35
  • Molecular Formula
    C17H32BrNO2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:69 mM;Water:198.7 mM
  • SMILES
    [Br-].CCCC(CCC)C(=O)O[C@@H]1C[C@@H]2CC[C@H](C1)[N+]2(C)C
  • Chemical Name
    [(1R5S)-88-dimethyl-8-azoniabicyclo[3.2.1]octan-3-yl] 2-propylpentanoate;bromide

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Freston JW et al. A double-blind evaluation of the nocturnal antisecretory effects of anisotropine methylbromide in man. Dose response and duration of action studies. J Clin Pharmacol. 1977 Jan;17(1):29-36.
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