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Nicotine Ditartrate
CAS No. 65-31-6
Nicotine Ditartrate( (?)-Nicotine Ditartrate )
Catalog No. M19822 CAS No. 65-31-6
( )-Nicotine is the dominant form of the natural alkaloid nicotine. It acts as an agonist of neuronal nicotinic acetylcholine receptors (nAChRs) and possesses addictive and teratogenic properties. ( )-(S)-Nicotine is significantly more active at binding nAChRs compared to the (+)-(R) antipode thus nicotine is typically synthesized as ( )-(S)-nicotine with only 0.2-1% of the (+)-(R) isomer present.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
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Biological Information
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Product NameNicotine Ditartrate
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NoteResearch use only, not for human use.
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Brief Description( )-Nicotine is the dominant form of the natural alkaloid nicotine. It acts as an agonist of neuronal nicotinic acetylcholine receptors (nAChRs) and possesses addictive and teratogenic properties. ( )-(S)-Nicotine is significantly more active at binding nAChRs compared to the (+)-(R) antipode thus nicotine is typically synthesized as ( )-(S)-nicotine with only 0.2-1% of the (+)-(R) isomer present.
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Description( )-Nicotine is the dominant form of the natural alkaloid nicotine. It acts as an agonist of neuronal nicotinic acetylcholine receptors (nAChRs) and possesses addictive and teratogenic properties. ( )-(S)-Nicotine is significantly more active at binding nAChRs compared to the (+)-(R) antipode thus nicotine is typically synthesized as ( )-(S)-nicotine with only 0.2-1% of the (+)-(R) isomer present.
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In Vitro——
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In Vivo——
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Synonyms(?)-Nicotine Ditartrate
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PathwayEndocrinology/Hormones
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TargetAChR
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RecptornAChR
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Research AreaOthers
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IndicationUlcerative colitis
Chemical Information
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CAS Number65-31-6
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Formula Weight462.41
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Molecular FormulaC18H26N2O12
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Purity>98% (HPLC)
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SolubilityDMSO:198.9 mM
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SMILESO[C@H]([C@@H](O)C(O)=O)C(O)=O.O[C@H]([C@@H](O)C(O)=O)C(O)=O.CN1CCC[C@H]1c1cccnc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Clayton P et al. The pyrolysis of (-)-(S)-nicotine: racemization and decomposition. Chirality. 2010 May 5;22(4):442-6.
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