Cart
sales@molnova.com
Alkannin
CAS No. 517-88-4
Alkannin( Shikonin )
Catalog No. M19808 CAS No. 517-88-4
Shikonin is a natural red naphthoquinone pigment has antimicrobial anti-tumor and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals cosmetics and some food products; shikonin also enters into the antiinflammatory ointment and cream compositions used for the treatment of burns.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 90 | In Stock |
|
| 10MG | 135 | In Stock |
|
| 50MG | 360 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
| 1 mL x 10 mM in DMSO | 44 | In Stock |
|
| 5MG | 30 | In Stock |
|
| 10MG | 41 | In Stock |
|
| 25MG | 64 | In Stock |
|
| 50MG | 88 | In Stock |
|
| 100MG | 128 | In Stock |
|
| 200MG | 183 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameAlkannin
-
NoteResearch use only, not for human use.
-
Brief DescriptionShikonin is a natural red naphthoquinone pigment has antimicrobial anti-tumor and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals cosmetics and some food products; shikonin also enters into the antiinflammatory ointment and cream compositions used for the treatment of burns.
-
DescriptionShikonin is a natural red naphthoquinone pigment has antimicrobial anti-tumor and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals cosmetics and some food products; shikonin also enters into the antiinflammatory ointment and cream compositions used for the treatment of burns. It can suppress the cell viability adhesion invasion and migratory ability of MGC-803 cells through TLR2- or NF-κB-mediated pathway.(In Vitro):(-)-Alkannin inhibits HCT-116 and SW-480 cells growth with IC50s of 2.38 and 4.53 μM, respectively.
-
In Vitro——
-
In Vivo——
-
SynonymsShikonin
-
PathwayPI3K/Akt/mTOR signaling
-
TargetPI3K
-
RecptorPI3Kα
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number517-88-4
-
Formula Weight288.3
-
Molecular FormulaC16H16O5
-
Purity>98% (HPLC)
-
SolubilityDMSO:10 mM
-
SMILESC\C(C)=C\C[C@H](O)C1=CC(=O)c2c(O)ccc(O)c2C1=O
-
Chemical Name(S)-58-Dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)-14-naphthoquinone
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Takano-Ohmuro H Yoshida L S Yuda Y et al. Shikonin inhibits IgE-mediated histamine release by human basophils and Syk kinase activity[J]. Inflammation Research 2008 57(10):484-488.
molnova catalog
related products
-
TGX-221
A potent, selective PI3K p110β inhibitor with IC50 of 8.5 nM.
-
ON 146040
ON 146040 is an effective inhibitor of PI3K isoforms with IC50s of 14 and 20 nM for PI3Kα and PI3Kδ, respectively.
-
ZSTK-474
A potent inhibitor of class I PI3K isoforms with IC50 of 17 nM, 53 nM, and 6 nM for p110β, p110γ, and p110δ, respectively.
