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Alkannin
CAS No. 517-88-4
Alkannin( Shikonin )
Catalog No. M19808 CAS No. 517-88-4
Shikonin is a natural red naphthoquinone pigment has antimicrobial anti-tumor and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals cosmetics and some food products; shikonin also enters into the antiinflammatory ointment and cream compositions used for the treatment of burns.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 44 | In Stock |
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| 5MG | 30 | In Stock |
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| 10MG | 41 | In Stock |
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| 25MG | 64 | In Stock |
|
| 50MG | 88 | In Stock |
|
| 100MG | 128 | In Stock |
|
| 200MG | 183 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAlkannin
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NoteResearch use only, not for human use.
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Brief DescriptionShikonin is a natural red naphthoquinone pigment has antimicrobial anti-tumor and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals cosmetics and some food products; shikonin also enters into the antiinflammatory ointment and cream compositions used for the treatment of burns.
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DescriptionShikonin is a natural red naphthoquinone pigment has antimicrobial anti-tumor and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals cosmetics and some food products; shikonin also enters into the antiinflammatory ointment and cream compositions used for the treatment of burns. It can suppress the cell viability adhesion invasion and migratory ability of MGC-803 cells through TLR2- or NF-κB-mediated pathway.(In Vitro):(-)-Alkannin inhibits HCT-116 and SW-480 cells growth with IC50s of 2.38 and 4.53 μM, respectively.
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In Vitro——
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In Vivo——
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SynonymsShikonin
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PathwayPI3K/Akt/mTOR signaling
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TargetPI3K
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RecptorPI3Kα
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Research Area——
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Indication——
Chemical Information
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CAS Number517-88-4
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Formula Weight288.3
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Molecular FormulaC16H16O5
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESC\C(C)=C\C[C@H](O)C1=CC(=O)c2c(O)ccc(O)c2C1=O
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Chemical Name(S)-58-Dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)-14-naphthoquinone
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Takano-Ohmuro H Yoshida L S Yuda Y et al. Shikonin inhibits IgE-mediated histamine release by human basophils and Syk kinase activity[J]. Inflammation Research 2008 57(10):484-488.
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