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Cefcapene Pivoxil Hydrochloride
CAS No. 147816-24-8
Cefcapene Pivoxil Hydrochloride( —— )
Catalog No. M19785 CAS No. 147816-24-8
Cefcapene Pivoxil is the pivalate ester prodrug form of cefcapene a semi-synthetic third-generation cephalosporin with antibacterial activity.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 10MG | 35 | In Stock |
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| 25MG | 55 | In Stock |
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| 50MG | 93 | In Stock |
|
| 100MG | 139 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameCefcapene Pivoxil Hydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionCefcapene Pivoxil is the pivalate ester prodrug form of cefcapene a semi-synthetic third-generation cephalosporin with antibacterial activity.
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DescriptionCefcapene Pivoxil is the pivalate ester prodrug form of cefcapene a semi-synthetic third-generation cephalosporin with antibacterial activity. After oral administration of cefcapene pivoxil the ester bond is cleaved releasing active cefcapene.(In Vivo):Cefcapene pivoxil hydrochloride hydrate (oral administration; 100mg/kg; 4 days) is effective against invasive BLNAR strains in mice lung, it stimates peak antibiotic concentrations of 1 to 2 μg/ml in the blood of mice from 30 to 120 min after intragastric administration.
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In Vitro——
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In VivoCefcapene pivoxil hydrochloride hydrate (oral administration; 100mg/kg; 4 days) is effective against invasive BLNAR strains in mice lung, it stimates peak antibiotic concentrations of 1 to 2 μg/ml in the blood of mice from 30 to 120 min after intragastric administration. Animal Model:Four-week-old female C57BL/6J mice with bacterial suspension in BSG (1×109 CFU)Dosage:100 mg/kg Administration:Oral administration; 100mg/kg; 4 days Result:Was against H. influenzae colonization in mouse lung.
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Synonyms——
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PathwayGPCR/G Protein
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TargetAntibacterial
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RecptorAntibacterial
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Research AreaInflammation/Immunology
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IndicationBacterial infections; Ophthalmic infections; Otorhinolaryngological infections; Respiratory tract infections; Skin and soft tissue infections
Chemical Information
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CAS Number147816-24-8
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Formula Weight622.12
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Molecular FormulaC23H29N5O8S2
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Purity>98% (HPLC)
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SolubilityDMSO: 90 mg/mL
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SMILESO.Cl.CC\C=C(/C(=O)N[C@H]1[C@H]2SCC(COC(N)=O)=C(N2C1=O)C(=O)OCOC(=O)C(C)(C)C)c1csc(N)n1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Murakami M. Masuda K. Utsunomiya R. Oda F. Namba C. & Sayama K. (2015). Cefcapene Pivoxil Hydrochloride Is a Potentially New Treatment for Palmoplantar Pustulosis with Pustulotic Arthro-Osteitis.?Dermatology?231(4) 304-311. doi: 10.1159/000439401
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