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Neotuberostemonine
CAS No. 143120-46-1
Neotuberostemonine( —— )
Catalog No. M19780 CAS No. 143120-46-1
Neotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruitment and M2 polarization of macrophages. Neotuberostemonine demonstrates antitussive properties in guinea pigs.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 200 | In Stock |
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| 10MG | 295 | In Stock |
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| 25MG | 498 | In Stock |
|
| 50MG | 710 | In Stock |
|
| 100MG | 963 | In Stock |
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| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
|
| 1 mL x 10 mM in DMSO | 100 | In Stock |
|
| 5MG | 126 | In Stock |
|
| 10MG | 187 | In Stock |
|
| 25MG | 315 | In Stock |
|
| 50MG | 440 | In Stock |
|
| 100MG | 597 | In Stock |
|
| 200MG | 804 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameNeotuberostemonine
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NoteResearch use only, not for human use.
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Brief DescriptionNeotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruitment and M2 polarization of macrophages. Neotuberostemonine demonstrates antitussive properties in guinea pigs.
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DescriptionNeotuberostemonine (NTS) is one of the main antitussive alkaloids in the root of Stemona tuberosa Lour it has a significant protective effect on bleomycin (BLM)-induced pulmonary fibrosis through suppressing the recruitment and M2 polarization of macrophages. Neotuberostemonine demonstrates antitussive properties in guinea pigs.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayImmunology/Inflammation
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TargetNOS
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RecptorNOS
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Research Area——
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Indication——
Chemical Information
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CAS Number143120-46-1
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Formula Weight375.5
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Molecular FormulaC22H33NO4
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESCC[C@H]1[C@H]2OC(=O)[C@@H](C)[C@H]2[C@@H]2C[C@@H]([C@@H]3C[C@H](C)C(=O)O3)N3CCCC[C@H]1[C@H]23
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1.Xiang J Cheng S Feng T et al. Neotuberostemonine attenuates bleomycin-induced pulmonary fibrosis by suppressing the recruitment and activation of macrophages[J]. International Immunopharmacology 2016 36:158-164.
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