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Home - Products - Proteasome/Ubiquitin - Endogenous Metabolite - 5'-DEOXYADENOSINE

5'-DEOXYADENOSINE

CAS No. 4754-39-6

5'-DEOXYADENOSINE( 5′-dAdo )

Catalog No. M19759 CAS No. 4754-39-6

5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genetic material which has long been of interest in understanding the mechanism of aging neurodegenerative diseases and carcinogenesis.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    5'-DEOXYADENOSINE
  • Note
    Research use only, not for human use.
  • Brief Description
    5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genetic material which has long been of interest in understanding the mechanism of aging neurodegenerative diseases and carcinogenesis.
  • Description
    5'-Deoxyadenosine is an oxidized nucleoside found in the urine of normal subjects. Oxidized nucleosides represent excellent biomarkers for determining the extent of damage in genetic material which has long been of interest in understanding the mechanism of aging neurodegenerative diseases and carcinogenesis. The normal form of deoxyadenosine used in DNA synthesis and repair is 2'-deoxyadenosine where the hydroxyl group (-OH) is at the 2' position of its ribose sugar moiety. 5'-deoxyadenosine has its hydroxyl group at the 5' position of the ribose sugar.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    5′-dAdo
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Human Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    4754-39-6
  • Formula Weight
    251.24
  • Molecular Formula
    C10H13N5O3
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM;Water:20mg/mL
  • SMILES
    C[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12
  • Chemical Name
    (2R3R4S5R)-2-(6-amino-9H-purin-9-yl)-5-methyltetrahydrofuran-34-diol

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Lee S H Jung B H Kim S Y et al. A rapid and sensitive method for quantitation of nucleosides in human urine using liquid chromatography/mass spectrometry with direct urine injection[J]. Rapid Communications in Mass Spectrometry 2004 18(9):973-977.
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