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Home - Products - Proteasome/Ubiquitin - Endogenous Metabolite - 2-Picolinic acid

2-Picolinic acid

CAS No. 98-98-6

2-Picolinic acid( PCL 016 )

Catalog No. M19678 CAS No. 98-98-6

PCL 016 is a topical antiviral agent which inhibits adenovirus replication in rabbit.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    2-Picolinic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    PCL 016 is a topical antiviral agent which inhibits adenovirus replication in rabbit.
  • Description
    PCL 016 is a topical antiviral agent which inhibits adenovirus replication in rabbit.(In Vivo):Topical 1.5% PCL, 0.8% PCL, 0.369% PCL (pH7), 0.369% PCL (pH4) and 0.5% CDV are significantly more effective than the Control in reducing Ad Positive Cultures/Total (Days 1-14) and the Duration of Ad Shedding in the Ad5/NZW rabbit ocular model. Although not statistically significant, there appears to be a trend toward concentration-dependent efficacy of Picolinic acid on the Duration of Ad Shedding. There is no apparent ocular toxicity associated with Picolinic acid concentrations.
  • In Vitro
    ——
  • In Vivo
    Topical 1.5% PCL, 0.8% PCL, 0.369% PCL (pH7), 0.369% PCL (pH4) and 0.5% CDV are significantly more effective than the Control in reducing Ad Positive Cultures/Total (Days 1-14) and the Duration of Ad Shedding in the Ad5/NZW rabbit ocular model. Although not statistically significant, there appears to be a trend toward concentration-dependent efficacy of Picolinic acid on the Duration of Ad Shedding. There is no apparent ocular toxicity associated with Picolinic acid concentrations.
  • Synonyms
    PCL 016
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Endogenous Metabolite
  • Research Area
    Endocrinology
  • Indication
    Acne

Chemical Information

  • CAS Number
    98-98-6
  • Formula Weight
    123.11
  • Molecular Formula
    C6H5NO2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM;Water:50 mg/mL
  • SMILES
    OC(=O)c1ccccn1
  • Chemical Name
    2-Pyridinecarboxylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Sreekumar A Poisson L M Rajendiran T M et al. Metabolomic profiles delineate potential role for sarcosine in prostate cancer progression.[J]. Nature 2009 457(7231):910-914.
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