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2'-Deoxycytidine monohydrate

CAS No. 951-77-9

2'-Deoxycytidine monohydrate( Cytosine deoxyriboside | Deoxycytidine | Deoxyribose cytidine | 2'-Deoxycytidine | Cytosine deoxyribonucleoside | 2(1H)-Pyrimidinone )

Catalog No. M19673 CAS No. 951-77-9

One of the principal nucleosides of DNA composed of cytosine and deoxyribose. A nucleoside consists of only a pentose sugar linked to a purine or pyrimidine base without a phosphate group.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    2'-Deoxycytidine monohydrate
  • Note
    Research use only, not for human use.
  • Brief Description
    One of the principal nucleosides of DNA composed of cytosine and deoxyribose. A nucleoside consists of only a pentose sugar linked to a purine or pyrimidine base without a phosphate group.
  • Description
    One of the principal nucleosides of DNA composed of cytosine and deoxyribose. A nucleoside consists of only a pentose sugar linked to a purine or pyrimidine base without a phosphate group. When N1 is linked to the C1 of deoxyribose deoxynucleosides and nucleotides are formed from cytosine and deoxyribose; deoxycytidine monophosphate (dCMP) deoxycytidine diphosphate (dCDP) deoxycytidine triphosphate (dCTP). CTP is the source of the cytidine in RNA (ribonucleic acid) and deoxycytidine triphosphate (dCTP) is the source of the deoxycytidine in DNA (deoxyribonucleic acid).
  • In Vitro
    ——
  • In Vivo
    Animal Model:Mice inoculated SP2/0 myeloma cells Dosage:25 mg/kg Administration:i.v., 4 times, from 8 days to 16 daysResult:Decreased the tumor weight and volume.Increased survival time.
  • Synonyms
    Cytosine deoxyriboside | Deoxycytidine | Deoxyribose cytidine | 2'-Deoxycytidine | Cytosine deoxyribonucleoside | 2(1H)-Pyrimidinone
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    951-77-9
  • Formula Weight
    227.22
  • Molecular Formula
    C9H13N3O4
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM;Water:50mg/mL
  • SMILES
    Nc1ccn([C@H]2C[C@H](O)[C@@H](CO)O2)c(=O)n1
  • Chemical Name
    4-amino-1-((2R4S5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Horn D et al. Inhibition of biological effects of bromodeoxyuridine by deoxycytidine: correlation with decreased incorporation of bromodeoxyuridine into DNA. Somatic Cell Genet. 1976 Sep;2(5):469-81.
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