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2'-Deoxyadenosine 5'-monophosphate

CAS No. 653-63-4

2'-Deoxyadenosine 5'-monophosphate( D-AMP )

Catalog No. M19653 CAS No. 653-63-4

Adenosine is a nucleoside comprised of adenine attached to a ribose (ribofuranose) moiety via a -N9-glycosidic bond. Deoxyadenosine monophosphate is a derivative of the common nucleic acid ATP or adenosine triphosphate in which the -OH (hydroxyl) group on the 2' carbon on the nucleotide's pentose has been removed (hence the deoxy- part of the name).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 48 In Stock
50MG 28 In Stock
100MG 42 In Stock
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Biological Information

  • Product Name
    2'-Deoxyadenosine 5'-monophosphate
  • Note
    Research use only, not for human use.
  • Brief Description
    Adenosine is a nucleoside comprised of adenine attached to a ribose (ribofuranose) moiety via a -N9-glycosidic bond. Deoxyadenosine monophosphate is a derivative of the common nucleic acid ATP or adenosine triphosphate in which the -OH (hydroxyl) group on the 2' carbon on the nucleotide's pentose has been removed (hence the deoxy- part of the name).
  • Description
    Adenosine is a nucleoside comprised of adenine attached to a ribose (ribofuranose) moiety via a -N9-glycosidic bond. Deoxyadenosine monophosphate is a derivative of the common nucleic acid ATP or adenosine triphosphate in which the -OH (hydroxyl) group on the 2' carbon on the nucleotide's pentose has been removed (hence the deoxy- part of the name). Additionally the monophosphate of the name indicates that two of the phosphoryl groups of GTP have been removed most likely by hydrolysis. Deoxyadenosine monophosphate is abbreviated dAMP..
  • In Vitro
    2′-Deoxyadenosine 5′-monophosphate (dAMP) is incorporated into Caco-2 cells in a time-dependent manner. The uptake of 2′-Deoxyadenosine 5′-monophosphate is increased with a drop in pH, suggesting that 2′-Deoxyadenosine 5′-monophosphate transport activity might be linked to the protons. 2′-Deoxyadenosine 5′-monophosphate uptake by Caco-2 cells is pH- and Na+-dependent.
  • In Vivo
    ——
  • Synonyms
    D-AMP
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    653-63-4
  • Formula Weight
    331.22
  • Molecular Formula
    C10H14N5O6P
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10 mM
  • SMILES
    Nc1ncnc2n(cnc12)[C@H]1C[C@H](O)[C@@H](COP(O)(O)=O)O1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Hohenester E Hutchinson W L Pepys M B et al. Crystal structure of a decameric complex of human serum amyloid P component with bound dAMP[J]. Journal of Molecular Biology 1997 269(4):0-578.
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