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3-Methylglutaric acid
CAS No. 626-51-7
3-Methylglutaric acid( —— )
Catalog No. M19647 CAS No. 626-51-7
Methylglutaric acid is a leucine metabolite. A large amount of methylglutaric acid is identified in urine of patients with deficiency of 3-methylglutaconyl coenzyme A hydratase. Methylglutaric acid is also found to be associated with 3-hydroxy-3-methylglutaryl-CoA lyase deficiency another inborn error of metabolism.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 28 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | 39 | In Stock |
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Biological Information
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Product Name3-Methylglutaric acid
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NoteResearch use only, not for human use.
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Brief DescriptionMethylglutaric acid is a leucine metabolite. A large amount of methylglutaric acid is identified in urine of patients with deficiency of 3-methylglutaconyl coenzyme A hydratase. Methylglutaric acid is also found to be associated with 3-hydroxy-3-methylglutaryl-CoA lyase deficiency another inborn error of metabolism.
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DescriptionMethylglutaric acid is a leucine metabolite. A large amount of methylglutaric acid is identified in urine of patients with deficiency of 3-methylglutaconyl coenzyme A hydratase (PMID 6181239 ). Methylglutaric acid is also found to be associated with 3-hydroxy-3-methylglutaryl-CoA lyase deficiency another inborn error of metabolism.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayProteasome/Ubiquitin
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TargetEndogenous Metabolite
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RecptorEndogenous Metabolite
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Research Area——
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Indication——
Chemical Information
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CAS Number626-51-7
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Formula Weight146.14
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Molecular FormulaC6H10O4
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Purity>98% (HPLC)
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SolubilityDMSO:10 mM
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SMILESCC(CC(O)=O)CC(O)=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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N1-Acetylspermidine ...
N1-Acetylspermidine hydrochloride, an acetyl derivative of spermidine, serves as a substrate for polyamine oxidase and selectively elevates its levels in human colorectal adenocarcinomas.
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3-Methyl-2-oxovaleri...
3-Methyl-2-oxovaleric acid is an abnormal metabolite that arises from the incomplete breakdown of branched-chain amino acids. 3-Methyl-2-oxovaleric acid is a neurotoxin an acidogen and a metabotoxin. A neurotoxin causes damage to nerve cells and nerve tissues.
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Spermidine
Spermidine inhibits NOS1 (nNOS). Spermidine binds and precipitates DNA and may be used for purification of DNA binding proteins. Spermidine activates PNK (polynucleotide kinase T4). Spermidine binds to and activates NMDA and has been shown to potentiate NMDA-induced currents in a concentration-dependent manner.
