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Creatine

CAS No. 57-00-1

Creatine( Methylguanidoacetic acid )

Catalog No. M19635 CAS No. 57-00-1

Creatine is an amino acid that occurs in vertebrate tissues and in urine. In muscle tissue creatine generally occurs as phosphocreatine.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Creatine
  • Note
    Research use only, not for human use.
  • Brief Description
    Creatine is an amino acid that occurs in vertebrate tissues and in urine. In muscle tissue creatine generally occurs as phosphocreatine.
  • Description
    Creatine is an amino acid that occurs in vertebrate tissues and in urine. In muscle tissue creatine generally occurs as phosphocreatine. Creatine is excreted as creatinine in the urine. Creatine functions as part of the cell's energy shuttle. The high energy phosphate group of ATP is transferred to creatine to form phosphocreatine in the following reaction: Cr + ATP <-> PCr + ADP. This reaction is reversibly catalyzed by creatine kinase. In the human body creatine is synthesized mainly in the liver by the use of parts from three different amino acids: arginine glycine and methionine. 95% of it is later stored in the skeletal muscles and the rest is stored in the brain heart and testes.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    Methylguanidoacetic acid
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Endogenous Metabolite
  • Research Area
    Neurological Disease
  • Indication
    Amyotrophic lateral sclerosis; Huntington's disease; Metabolic disorders; Neuromuscular disorders; Parkinson's disease

Chemical Information

  • CAS Number
    57-00-1
  • Formula Weight
    131.13
  • Molecular Formula
    C4H9N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO:10uM;Water:24 mg/mL(183 mM)
  • SMILES
    CN(CC(O)=O)C(N)=N
  • Chemical Name
    Glycine N-(aminoiminomethyl)-N-methyl-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Subramanian A Gupta A Saxena S et al. Proton MR CSF analysis and a new software as predictors for the differentiation of meningitis in children[J]. NMR in biomedicine 2005 18(4):213-225.
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