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4-Methylcatechol

CAS No. 452-86-8

4-Methylcatechol( p-Methylcatechol | 34-Dihydroxytoluene | Homocatechol | 4-methylbenzene-12-diol )

Catalog No. M19606 CAS No. 452-86-8

4-methylcatechol is a metabolite of homoprotocatechuic acid. It is both a substrate and a suicide inhibitor of Catechol 23-dioxygenase. 4-methylcatechol is known to induce the production of brain-derived neurotrophic factor (BDNF). Recent studies have suggested that a lack of brain-derived neurotrophic factor (BDNF) in the limbic system may cause neuropathic pain.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 34 In Stock
100MG 31 In Stock
200MG Get Quote In Stock
500MG 75 In Stock
1G 110 In Stock
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Biological Information

  • Product Name
    4-Methylcatechol
  • Note
    Research use only, not for human use.
  • Brief Description
    4-methylcatechol is a metabolite of homoprotocatechuic acid. It is both a substrate and a suicide inhibitor of Catechol 23-dioxygenase. 4-methylcatechol is known to induce the production of brain-derived neurotrophic factor (BDNF). Recent studies have suggested that a lack of brain-derived neurotrophic factor (BDNF) in the limbic system may cause neuropathic pain.
  • Description
    4-methylcatechol is a metabolite of homoprotocatechuic acid. It is both a substrate and a suicide inhibitor of Catechol 23-dioxygenase. 4-methylcatechol is known to induce the production of brain-derived neurotrophic factor (BDNF). Recent studies have suggested that a lack of brain-derived neurotrophic factor (BDNF) in the limbic system may cause neuropathic pain.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    p-Methylcatechol | 34-Dihydroxytoluene | Homocatechol | 4-methylbenzene-12-diol
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Catechol 23-Dioxygenase
  • Research Area
    Neurological Disease
  • Indication
    Diabetic neuropathies; Neuropathic pain

Chemical Information

  • CAS Number
    452-86-8
  • Formula Weight
    124.14
  • Molecular Formula
    C7H8O2
  • Purity
    >98% (HPLC)
  • Solubility
    DMSO: 10 mM;Water: Soluble;Ethanol: Soluble
  • SMILES
    Cc1ccc(O)c(O)c1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Okuta A et al. Construction of chimeric catechol 23-dioxygenase exhibiting improved activity against the suicide inhibitor 4-methylcatechol. Appl Environ Microbiol. 2004 Mar;70(3):1804-10.
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