Cart
sales@molnova.com
Home - Products - Others - Other Targets - Lawsone

Lawsone

CAS No. 83-72-7

Lawsone( Lawsone )

Catalog No. M19160 CAS No. 83-72-7

Lawsone (2-hydroxy-1,4-naphthoquinone), also known as hennotannic acid, is a red-orange dye present in the leaves of the henna plant (Lawsonia inermis) as well as in the flower of water hyacinth (Eichhornia crassipes).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 46 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG 41 In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    Lawsone
  • Note
    Research use only, not for human use.
  • Brief Description
    Lawsone (2-hydroxy-1,4-naphthoquinone), also known as hennotannic acid, is a red-orange dye present in the leaves of the henna plant (Lawsonia inermis) as well as in the flower of water hyacinth (Eichhornia crassipes).
  • Description
    Lawsone is a molluscacide from leaves of Lawsonia inermis L. topical sunscreening agent; powdered leaves of Lawsonia inermis(Lythraceae) used as brown hair dye.
  • In Vitro
    Cell Proliferation Assay Cell Line:DLD-1, MRC-5 Concentration:0.5, 1, 1.5, 2 mg/mL Incubation Time:24-96 h Result:Demonstrated significant suppression at concentration 2 mg/ml on DLD-1 cells and exhibited no suppression on normal fibroblast MRC-5 cells.Western Blot Analysis Cell Line:DLD-1 Concentration:0.5, 1, 1.5, 2 mg/mL Incubation Time:48 h Result:Decreased the level of both proteins cyclin B1 and cdk1. Exhibited a dose-dependent effect on translocation of p65 of cytosol to the nucleus.
  • In Vivo
    Animal Model:Female rat model (10-11- week-old)Dosage:62.5, 125, 250, 500, 750 μmol/kg/day Administration:p.o.Result:Increased the levels of ALT、AST、GLDH、LDH、HBDH、urea and creatinine at a dose of 500 or 750 μmol/kg/day.Animal Model:Rat model of colon cancer Dosage: 200 mg/mL Administration:p.o.Result:Reduced the tumor diameters and decreased multiplicity of these adenomas.
  • Synonyms
    Lawsone
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    83-72-7
  • Formula Weight
    174.16
  • Molecular Formula
    C10H6O3
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (574.22 mM)
  • SMILES
    c1ccc2c(c1)C(=O)C(=CC2=O)O
  • Chemical Name
    1,4-Naphthalenedione, 2-hydroxy-

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Munt DJ, et al. AAPS PharmSciTech. 2015 Dec;16(6):1425-33.
Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog
related products

  • Ammonium formate

    Formic acid is the simplest carboxylic acid. Formate is an intermediate in normal metabolism. It is responsible for both metabolic acidosis and disrupting mitochondrial electron transport and energy production by inhibiting cytochrome oxidase activity the terminal electron acceptor of the electron transport chain.

  • 3,5-Di-O-caffeoylqui...

    3,5-Di-O-caffeoylquinic acid methyl ester exhibits potent inhibitory activities against the formation of advanced glycation end products (AGEs); it exhibits cytotoxicity actions against human cervix carcinoma HeLa cells. 3,5-Di-O-caffeoylquinic acid methyl ester shows high efficiency and low toxicity with antivirus activity against RSV.

  • Schisandrin

    Schisandrin is a compound with anti-asthmatic, anti-cancer, and anti-inflammatory effects.

Sign In Join Free