Cart
sales@molnova.com
Z-VAD(OH)-FMK
CAS No. 161401-82-7
Z-VAD(OH)-FMK( Z-VAD | Caspase Inhibitor VI )
Catalog No. M19461 CAS No. 161401-82-7
Z-VAD-FMK (Caspase Inhibitor VI) is an irreversible pan-caspase inhibitor.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 269 | In Stock |
|
| 5MG | 244 | In Stock |
|
| 10MG | 416 | In Stock |
|
| 25MG | 661 | In Stock |
|
| 50MG | 920 | In Stock |
|
| 100MG | 1237 | In Stock |
|
| 200MG | 1655 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameZ-VAD(OH)-FMK
-
NoteResearch use only, not for human use.
-
Brief DescriptionZ-VAD-FMK (Caspase Inhibitor VI) is an irreversible pan-caspase inhibitor.
-
DescriptionZ-VAD-FMK (Z-VAD(OH)-FMK) is a well-know pan caspase inhibitor which does not inhibit ubiquitin carboxy-terminal hydrolase L1 (UCHL1) activity even at concentrations as high as 440 μM.
-
In VitroCell Viability Assay Cell Line:HeLa cells Concentration:40 μM Incubation Time:Prtreated for 30 minutes Result:Prevented TSSLT-induced cell death. More than 80% cell survival was observed.
-
In Vivo——
-
SynonymsZ-VAD | Caspase Inhibitor VI
-
PathwayApoptosis
-
TargetCaspase
-
RecptorCaspase-8
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number161401-82-7
-
Formula Weight453.46
-
Molecular FormulaC21H28FN3O7
-
Purity>98% (HPLC)
-
SolubilityDMSO:83 mg/mL (183 mM);Ethanol:83 mg/mL (183 mM);Water:<1 mg/mL
-
SMILESCC(C)[C@H](NC(=O)OCC1=CC=CC=C1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(O)=O)C(=O)CF
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1.Garcia-Calvo M et al. J Biol Chem. 1998 273(49) 32608-32613.
molnova catalog
related products
-
Gardenin B
Gardenin B exhibits superior antiproliferative activity against lung, breast, colon, hepatic and leukaemia cell lines as well as in keratinocytes .
-
Puerarin 6''-O-Xylos...
Puerarin 6''-O-xyloside possesses significant anti-osteoporotic activity on ovariectomy mice it has significant antitumour activities the mechanisms are related to increased levels of caspase-3 caspase-7 caspase-9 and Bax and reduced levels Bcl-2.
-
TCEP HCl
Tris(2-carboxyethyl)phosphine hydrochloride may be employed as a catalyst for the reduction of sulfoxides, sulfonyl chlorides, N-oxides, and azides.
