VBIT-4 ( VBIT-4 | VBIT 4 | VBIT4 )

Catalog No. M19386 CAS No. 2086257-77-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

VBIT-4
Note

Research use only, not for human use.
Brief Description

VBIT-4 is an inhibitor of VDAC1 the outer mitochondrial membrane protein known as voltage-dependent anion channel 1. VBIT-4 inhibits VDAC1 oligomerization apoptosis and mitochondrial dysfunction.
Description

VBIT-4 is an inhibitor of VDAC1 the outer mitochondrial membrane protein known as voltage-dependent anion channel 1. VBIT-4 inhibits VDAC1 oligomerization apoptosis and mitochondrial dysfunction.
In Vitro

——
In Vivo

——
Synonyms

VBIT-4 | VBIT 4 | VBIT4
Pathway

Metabolic Enzyme/Protease
Target

Other Targets
Recptor

Kd: 17 μM (VDAC1)
Research Area

——
Indication

——

CAS Number

2086257-77-2
Formula Weight

457.88
Molecular Formula

C21H23ClF3N3O3
Purity

>98% (HPLC)
Solubility

DMSO : 125 mg/mL (273.00 mM; Need ultrasonic)
SMILES

OCC(N1CCN(C2=CC=C(OC(F)(F)F)C=C2)CC1)CC(NC3=CC=C(Cl)C=C3)=O
Chemical Name

N-(4-chlorophenyl)-4-hydroxy-3-(4-(4-(trifluoromethoxy)phenyl)piperazin-1-yl)butanamide

1: Ben-Hail D et al. J Biol Chem. 2016 Nov 25;291(48):24986-25003. Epub 2016 Oct 13. PubMed PMID: 27738100; PubMed Central PMCID: PMC5122769.

Calculator

molnova catalog