Corylin( —— )

Catalog No. M19328 CAS No. 53947-92-5

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Corylin
Note

Research use only, not for human use.
Brief Description

Corylin is a major bioactive compound isolated from Psoralea corylifolia L; it has the activity of antibiotic or anticancer.
Description

Corylin is a major bioactive compound isolated from Psoralea corylifolia L; it has the activity of antibiotic or anticancer.
In Vitro

Western Blot Analysis Cell Line:HepG2 and Huh7 cells Concentration:3-30 μM Incubation Time:24-48 h Result:Reduced the expression of EMT-promoting proteins such as N-cadherin, vimentin, slug, and twist.
In Vivo

Animal Model:HFD- and DIO-treated miceDosage:50-100 mg/kg Administration:Oral gavage (p.o.), daily, 9 weeks Result:Reduced the weight of subcutaneous, visceral WAT, and body.Decreased the size of WAT adipocyte. Increased insulin sensitivity, mitochondrial biogenesis, and β-oxidation.Reduced serum levels of insulin and leptin and improved HOMA-IR.
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

MMP
Recptor

Others
Research Area

Cancer
Indication

——

1.Lee SW, et al. Phenolic compounds isolated from Psoralea corylifolia inhibit IL-6-induced STAT3 activation. Planta Med. 2012 Jun;78(9):903-6.

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