Hinokiflavone( —— )

Catalog No. M23871 CAS No. 19202-36-9

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Get Quotation Bulk Inquiry Add to Cart

Product Name

Hinokiflavone
Note

Research use only, not for human use.
Brief Description

Hinokiflavone is a novel modulator of pre-mRNA splicing activity in vitro and in cellulo.
Description

Hinokiflavone is a novel modulator of pre-mRNA splicing activity in vitro and in cellulo. Hinokiflavone blocks splicing of pre-mRNA substrates by inhibiting spliceosome assembly, specifically preventing B complex formation. Hinokiflavone is a SUMO protease inhibitor, inhibiting sentrin-specific protease 1 (SENP1) activity.Hinokiflavone has significant cytotoxicity, it has inhibition of MMP-9.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Metabolic Enzyme/Protease
Target

MMP
Recptor

MMP|bax|bcL-2
Research Area

——
Indication

——

CAS Number

19202-36-9
Formula Weight

538.5
Molecular Formula

C30H18O10
Purity

>98% (HPLC)
Solubility

DMSO:10 mM
SMILES

O=C1C=C(C2=CC=C(O)C=C2)OC3=CC(O)=C(OC4=CC=C(C5=CC(C6=C(O)C=C(O)C=C6O5)=O)C=C4)C(O)=C13
Chemical Name

——

1.Hinokiflavone, a cytotoxic principle from Rhus succedanea and the cytotoxicity of the related biflavonoids. Planta Med. 1989 Apr;55(2):166-8.

Calculator

molnova catalog