MS049 2HCl

CAS No. ——

MS049 2HCl ( —— )

Catalog No. M19312 CAS No. ——

MS049 is a potent and selective inhibitor of PRMT4 (IC50 = 34 nM) and PRMT6 (IC50 = 43 nM).

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 47 Get Quote
10MG 75 Get Quote
25MG 161 Get Quote
50MG 303 Get Quote
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Biological Information

  • Product Name
    MS049 2HCl
  • Note
    Research use only, not for human use.
  • Brief Description
    MS049 is a potent and selective inhibitor of PRMT4 (IC50 = 34 nM) and PRMT6 (IC50 = 43 nM).
  • Description
    MS049 is a potent and selective inhibitor of PRMT4 (IC50 = 34 nM) and PRMT6 (IC50 = 43 nM). It is less active against additional type I PRMTs (IC50s = >130, >220, and 1.6 μM for PRMT1, PRMT3, and PRMT8, respectively) and displays no inhibition against type II or type III PRMTs nor any additional methyltransferases or nonepigenetic targets tested.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    PRMT4| PRMT6
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    ——
  • Formula Weight
    321.28
  • Molecular Formula
    C15H26Cl2N2O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    Cl.Cl.CNCCN1CCC(CC1)OCc2ccccc2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Shen Y, etal. Journal of Medicinal Chemistry, 2016, 59(19):9124-9139.
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