Apafant( —— )

Catalog No. M33267 CAS No. 105219-56-5

Apafant (WEB 2086) is a highly potent platelet activating factor (PAF) antagonist that blocks eosinophil activation and can be used to study experimental allergic conjunctivitis in guinea pigs.

Purity : >98% (HPLC)

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Datasheet

HNMR

HPLC

MSDS

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Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	141	In Stock
5MG	140	In Stock
10MG	224	In Stock
25MG	443	In Stock
100MG	Get Quote	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

Apafant
Note

Research use only, not for human use.
Brief Description

Apafant (WEB 2086) is a highly potent platelet activating factor (PAF) antagonist that blocks eosinophil activation and can be used to study experimental allergic conjunctivitis in guinea pigs.
Description

Apafant (WEB 2086), a potent platelet-activating factor (PAF) antagonist, inhibits PAF binding to human PAF receptors with a Ki of 9.9 nM.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

PAFR
Research Area

——
Indication

——

Chemical Information

CAS Number

105219-56-5
Formula Weight

455.96
Molecular Formula

C22H22ClN5O2S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 40 mg/mL (87.73 mM )
SMILES

O=C(N1CCOCC1)CCC=2SC3=C(C2)C(=NCC4=NN=C(N43)C)C=5C=CC=CC5Cl
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Kato M, et al. Apafant, a potent platelet-activating factor antagonist, blocks eosinophil activation and is effective in the chronic phase of experimental allergic conjunctivitis in guinea pigs. J Pharmacol Sci. 2004 Aug;95(4):435-42.?

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