Detomidine HCl

Research use only, not for human use.

Detomidine HCl produce dose-dependent sedative and analgesic effects, mediatated by activation of α2 catecholamine receptors.

Detomidine HCl is an alpha2-Adrenoreceptor agonist with sedative properties.(In Vitro):Currently, detomidine is only licenced for use in horses. α2-adrenergic agonists produce dose-dependent analgesic effects, mediatated by activation of α2 catecholamine receptors, thus inducing a negative feedback response, reducing production of excitatory neurotransmitters. Due to inhibition of the sympathetic nervous system, detomidine also has cardiac and respiratory effects and an antidiuretic action.

Currently, detomidine is only licenced for use in horses. α2-adrenergic agonists produce dose-dependent analgesic effects, mediatated by activation of α2 catecholamine receptors, thus inducing a negative feedback response, reducing production of excitatory neurotransmitters. Due to inhibition of the sympathetic nervous system, detomidine also has cardiac and respiratory effects and an antidiuretic action.

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Detomidine hydrochloride | Detomidine HCl | MPV253

Cell Cycle/DNA Damage

HDAC

α2 catecholamine receptors

Neurological Disease

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90038-01-0

222.71

C12H14N2·HCl

>98% (HPLC)

DMSO : ≥ 100 mg/mL 449.01 mM H2O : 20 mg/mL 89.80 mM

Cl.CC1=C(C)C(CC2=CNC=N2)=CC=C1

5-[(2,3-Dimethylphenyl)methyl]-1H-imidazole hydrochloride

(-20℃)

With Ice Pack

≥ 2 years