Columbianetin is a new phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage it also has antifungal activity. Columbianetin has anti-inflammatory effects it promotes histamine release and inhibits the histamine release by substance P suggests that it may be helpful in regulating mast cell-mediated allergic inflammatory responses. (2'S)-columbianetin can be effectively used to protect keratinocytes from UVB induced damage.

Cinobufagin is a selective Na+/K+-ATPase inhibitor. The activity of Cinobufagin is same as ouabain.

Picroside I, a hepatoprotective agent, is reported to be antimicrobial and used against hepatitis B.