Ganoderic acid A( —— )

Catalog No. M19142 CAS No. 81907-62-2

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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Product Name

Ganoderic acid A
Note

Research use only, not for human use.
Brief Description

Ganoderic acid A exhibits antitumor activity, mediated through its inhibitory effect on nuclear transcription factor-kappaB and activator protein-1.
Description

Ganoderic acids are a class of closely related triterpenoids (derivatives from lanosterol) found in Ganoderma mushrooms. For thousands of years, the fruiting bodies of Ganoderma fungi have been used in traditional medicines in East Asia. Consequently, there have been efforts to identify the chemical constituents that may be responsible for the putative pharmacological effects. There are dozens of ganoderic acids that have been isolated and characterized, of which ganoderic acid A and ganoderic acid B are the most well characterized. Some ganoderic acids have been found to possess biological activities including hepatoprotection, anti-tumor effects, and 5-alpha reductase inhibition.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Apoptosis
Target

IL Receptor
Recptor

NF-κB
Research Area

Cancer
Indication

——

CAS Number

81907-62-2
Formula Weight

516.67
Molecular Formula

C30H44O7
Purity

>98% (HPLC)
Solubility

DMSO : ≥ 29 mg/mL; 56.13 mM
SMILES

CC(CC(=O)CC(C)C(=O)O)C1CC(C2(C1(CC(=O)C3=C2C(CC4C3(CCC(=O)C4(C)C)C)O)C)C)O
Chemical Name

(25R)-7β,15α-Dihydroxy-3,11,23-trioxo-5α-lanost-8-en-26-oic acid