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Aurantio-obtusin
CAS No. 67979-25-3
Aurantio-obtusin( —— )
Catalog No. M18988 CAS No. 67979-25-3
Aurantio-obtusin is a promising osteoanabolic compound of natural origin with potential therapeutic applications in the prevention of osteoporosis and other metabolic bone diseases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 50 | In Stock |
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| 2MG | 31 | In Stock |
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| 5MG | 48 | In Stock |
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| 10MG | 67 | In Stock |
|
| 25MG | 107 | In Stock |
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| 50MG | 152 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAurantio-obtusin
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NoteResearch use only, not for human use.
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Brief DescriptionAurantio-obtusin is a promising osteoanabolic compound of natural origin with potential therapeutic applications in the prevention of osteoporosis and other metabolic bone diseases.
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DescriptionBiotransformation of glucoAurantio-obtusin towards Aurantio-obtusin increased the toxicity of irinotecan through increased inhibition of SN-38 glucuronidation. Aurantio-obtusin, stimulated chemotactic migration of MC3T3-E1 osteoblast cells in a concentration-dependent manner. Besides migration, the compound stimulated osteoblast differentiation and mineralization. Aurantio-obtusin is a promising osteoanabolic compound of natural origin with potential therapeutic applications in the prevention of osteoporosis and other metabolic bone diseases.
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In Vitro——
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In VivoAnimal Model:C57BL/6J mice model Dosage:5 mg/kg, 10 mg/kg, 15 mg/kg Administration:Oral gavage (p.o.), feeding with HFSW diet for 4 weeks then giving different dose of Aurantio-obtusin for another 4 weeks. Result:Decreased the levels of TG and TC in liver and TG, ALT and AST in serum induced by HSFW.Reduced the number and size of fat droplets in liver cells.Significantly increased AMPK phosphorylation in HFSW-induced mice.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research AreaOthers-Field
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Indication——
Chemical Information
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CAS Number67979-25-3
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Formula Weight330.29
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Molecular FormulaC17H14O7
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 25 mg/mL (75.69 mM)
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SMILESCC1=C(C(=C2C(=C1)C(=O)C3=CC(=C(C(=C3C2=O)O)OC)O)OC)O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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